OpenAI Blog

Scientific computing in the age of agentic AI

A new field report shows how scientists use AI coding agents to modernize scientific computing, accelerating software development and discovery in genomics and beyond.

Hugging Face Trending Papers
Jun 22

AI Scientists as Engines of Discovery: A Case for Development within Reformed Institutions

Agentic artificial intelligence (AI) systems are beginning to assist, accelerate, and partially automate scientific discovery, performing tasks that span literature synthesis, code generation, data analysis, hypothesis proposal, and model criticism. We argue that this transition is qualitative rather than incremental, and that suitably designed multi-agent systems may evolve from passive computational tools into ``AI scientists'' that can expand the hypothesis-generating and verification capacity of science.

arXiv AI
1d ago

Position: AI Agents in Scientific Teams Should Be Studied as Human-Agent Systems

arXiv:2608. 14667v1 Announce Type: new Abstract: Large language model-based agents are increasingly deployed as collaborators in scientific discovery yet most current work focuses on the autonomous capabilities of "AI Scientists".

By Patrick Emami, Sameera Horawalavithana, Truc Nguyen, Gihan Panapitiya, Bruno Jacob, Siddhisanket Raskar, Saumya Sinha, Jared D. Willard, Andrew Glaws, Nithin Somasekharan, Ling Yue, Brian Lu, Shaowu Pan, Jason Eisner
arXiv AI
Jul 7

LLMoxie: Exploring Agentic AI for Scientific Software Development

arXiv:2607. 02703v1 Announce Type: cross Abstract: In this paper, we describe LLMoxie, an institutional AI platform whose three-tiered architecture supports multi-cloud and on-premise inference, a LiteLLM/MLflow control plane for authentication, budgeting, PII masking, and observability, and an application augmentation layer for AI coding agents.

By Landung Setiawan, Anant Mittal, Cordero Core, Anshul Tambay, Carlos Garcia Jurado Suarez, David A. C. Beck, Andrew J. Connolly, Vani Mandava
arXiv AI
Jun 9

EvoMaster: A Foundational Evolving Agent Framework for Agentic Science at Scale

arXiv:2604. 17406v3 Announce Type: replace Abstract: The convergence of large language models and agents is catalyzing a new era of scientific discovery: Agentic Science.

By Xinyu Zhu, Yuzhu Cai, Zexi Liu, Cheng Wang, Fengyang Li, Wenkai Jin, Wanxu Liu, Zehao Bing, Bingyang Zheng, Jingyi Chai, Shuo Tang, Rui Ye, Yuwen Du, Xianghe Pang, Yaxin Du, Tingjia Miao, Yuzhi Zhang, Ruoxue Liao, Zhaohan Ding, Linfeng Zhang, Yanfeng Wang, Weinan E, Siheng Chen