Multimarginal flow matching with optimal transport potentials
arXiv:2606. 05327v1 Announce Type: new Abstract: Flow matching (FM) has emerged as a powerful framework for learning dynamic transport maps between two empirical distributions.
The paper introduces Distribution‑Conditioned Transport (DCT), a framework that learns transport maps conditioned on embeddings of source and target distributions, allowing generalization to unseen distribution pairs. DCT supports semi‑supervised learning for distributional forecasting by leveraging distributions observed at only one condition. It is agnostic to the transport mechanism and is demonstrated on synthetic benchmarks and four biological applications, including batch effect transfer in single‑cell genomics and modeling T‑cell receptor sequence evolution.
arXiv:2606. 05327v1 Announce Type: new Abstract: Flow matching (FM) has emerged as a powerful framework for learning dynamic transport maps between two empirical distributions.
The paper introduces COFM, a framework for consistent optimal transport flow matching that uses partially input convex neural networks (PICNN) to parameterize the transport potential. By adding a Hamilton‑Jacobi residual to the training objective, COFM enforces dynamical consistency and supports both one‑step transport and multi‑step ODE sampling without costly inner optimization. Experiments on benchmark datasets show that COFM achieves competitive performance while reducing L^2‑UVP by over 2× and cutting computational time by about 9× compared to state‑of‑the‑art models.
arXiv:2602. 01179v2 Announce Type: replace Abstract: Gradual domain adaptation (GDA) aims to mitigate domain shift by progressively adapting models from the source domain to the target domain via intermediate domains.
The paper introduces BROT, a two‑step approach for estimating optimal transport maps. First, it computes the unregularized OT plan, then fits a deep neural network to the resulting barycentric targets using least‑squares regression. The authors prove that, under standard regularity conditions, BROT achieves the minimax convergence rate when the true OT map is Lipschitz, and demonstrate its effectiveness on synthetic data, images, and downstream tasks such as single‑cell perturbation prediction and unsupervised domain adaptation.
Particle-based variational inference (ParVI) methods approximate an intractable target distribution by evolving an ensemble of interacting samples. Existing approaches rely predominantly on kernel-based repulsion (e.
arXiv:2606. 14023v1 Announce Type: cross Abstract: Optimal Transport has become recently a powerful method for domain adaptation by aligning source and target distributions.
Many modern generative modeling methods, including diffusion models, normalizing flows, and flow matching, estimate transport maps or plans between distributions without explicitly targeting an optimal transport (OT) map. In applications like generative modeling, the transport cost itself is irrelevant, and this makes it natural to target maps which are more tractable from either a statistical or computational standpoint.
arXiv:2606. 08802v1 Announce Type: new Abstract: Standard flow and diffusion pre-training matches the distribution of available data (e.
arXiv:2606. 30574v1 Announce Type: new Abstract: Many modern generative modeling methods, including diffusion models, normalizing flows, and flow matching, estimate transport maps or plans between distributions without explicitly targeting an optimal transport (OT) map.
arXiv:2608. 14293v1 Announce Type: cross Abstract: High-content microscopy enables systematic profiling of cellular responses to chemical perturbations, but the scale of the chemical space makes exhaustive phenotypic characterization experimentally infeasible.
arXiv:2601. 08379v2 Announce Type: replace-cross Abstract: Pre-trained diffusion models have emerged as powerful generative priors for both unconditional and conditional sample generation, yet their outputs often deviate from the characteristics of user-specific target data.
arXiv:2602.19600v2 Announce Type: replace Abstract: Many high-dimensional datasets concentrate near a low-dimensional structure embedded in the ambient space. Generative models for such data must con...