The paper introduces SCR-MF, a two‑stage workflow for single‑cell RNA sequencing imputation that first detects dropout events with scRecover and then imputes missing values using the non‑parametric missForest algorithm. Benchmarking on public and simulated datasets shows that SCR‑MF delivers robust, interpretable results that match or surpass existing methods while maintaining biological fidelity. Runtime analysis indicates that SCR‑MF balances accuracy with computational efficiency, making it well suited for mid‑scale single‑cell studies.
By Ali Anaissi, Deshao Liu, Yuanzhe Jia, Weidong Huang, Widad Alyassine, Junaid Akram
The paper introduces a pre‑training pipeline that creates transformer‑based imputation specialists for tabular data with specific missingness patterns. By featurizing entries, generating synthetic data with configurable missingness modules, and fitting on millions of synthetic tables, the pipeline produces pattern‑specific models that outperform dedicated methods for each missingness pattern. A default model trained only on MCAR data, TabImpute, remains robust across all tested patterns, and the authors release the pipeline, models, and a new benchmark of 42 datasets and 11 missingness patterns.
By Jacob Feitelberg, Dwaipayan Saha, Kyuseong Choi, Zaid Ahmad, Anish Agarwal, Raaz Dwivedi
arXiv:2609.39613v1 Announce Type: new
Abstract: Missing data are a fundamental challenge in statistical analysis and machine learning, as the choice of imputation method substantially impacts downstr...
By Jinwei Li, Michelle Bruch, Daniel Tenbrinck
arXiv:2607. 05613v1 Announce Type: new Abstract: Clinical care often relies on key laboratory indicators, yet real-world patient visits are sparse and tests are ordered irregularly, leading to pervasive missingness.
By Xinrui He, Mengting Ai, Junting Wang, Curtiss B. Cook, Jingrui He
arXiv:2607. 07725v1 Announce Type: cross Abstract: Genomic prediction models often fail to transfer across institutions because sequencing panels differ across sites, creating structural feature missingness at deployment.
By Muhammet Sami Yavuz, Ayhan Can Erdur, Sabri Mustafa Kahya, Benedikt Wiestler, Jana Lipkova
arXiv:2606. 05073v1 Announce Type: new Abstract: Missing value imputation is a fundamental task in machine learning, with most existing methods assuming that all missing entries correspond to unobserved regular values.
By Lixing Zhang, Yidong Ouyang, Weifu Li, Shixiang Zhu, Guang Cheng, Liyan Xie
Missing value imputation is a fundamental task in machine learning, with most existing methods assuming that all missing entries correspond to unobserved regular values. In many real-world datasets, however, missingness may arise from two distinct sources: some entries are meaningfully missing (intrinsically absent and semantically valid), while others are missing due to the observation process and should be imputed.
Fed-ReMasker is a federated learning approach that adapts the ReMasker masked autoencoder for tabular data imputation, specifically addressing feature-level missingness where entire features are absent at some centers. The method enables centers to impute unobserved features by leveraging knowledge from collaborating institutions. In benchmark tests on synthetic and real-world datasets, Fed-ReMasker achieves the lowest imputation error in the majority of scenarios and remains robust to client heterogeneity, closely matching the performance of a centralized model.
By Ioannis Papathanail, Rooholla Poursoleymani, Lubnaa Abdur Rahman, Stavroula Georgia Mougiakakou
arXiv:2607. 06930v1 Announce Type: cross Abstract: Missing data is prevalent in practical applications, making effective imputation an essential preprocessing step for downstream analysis.
By Chuyao Zhang, E Li, Taochen Chen, Yiqun Zhang, Yuzhu Ji, Shuping Zhao, Peng Liu, Yiu-ming Cheung
arXiv:2609.15284v1 Announce Type: new
Abstract: Missing values are ubiquitous in heterogeneous data mining, where numerical, categorical, and binary variables often coexist. Many imputation methods,...
By Sergei Kholkin, Kirill Sokolov, Dmitry Baranchuk, Evgeny Burnaev, Alexander Korotin
arXiv:2609.37632v1 Announce Type: cross
Abstract: Time series imputation has progressed from statistical and deep learning approaches to diffusion-based models, which have shown strong recent perform...
By Fariza Rashid, Duc Van Le, Rahat Masood, Gustavo Batista, Aruna Seneviratne, Suranga Seneviratne
arXiv:2606. 06328v1 Announce Type: new Abstract: In healthcare, multimodal time series tasks often operate on incomplete observations in practice, for example when ECG segments are lost because electrodes detach or an entire respiratory channel is unavailable during overnight monitoring.
By Ziwen Kan, Wugeng Zheng, Tianlong Chen, Song Wang