CogDrift-4D introduces a hierarchical 4D Transformer framework for detecting mild cognitive impairment (MCI) by modeling temporal behavioral decay across seven unscripted multimodal interactions over 18 months. The approach represents continuous, multi‑session data as a dense 4D tensor and employs dual‑level modeling: intra‑session least‑squares regression to capture acute fading of facial and acoustic features, and an inter‑session recursive cross‑attention encoder to accumulate cumulative fatigue. A localized Quality Gate filters low‑integrity features, and early fusion integrates semantic and raw dynamics, achieving an MCI classification accuracy of 0.733 ± 0.13 and an F1‑score of 0.716 ± 0.14, surpassing advanced baselines.
arXiv:2609.14764v1 Announce Type: cross Abstract: Early detection of cognitive decline from speech offers a scalable and non-invasive alternative to conventional clinical assessment. Verbal fluency t...
arXiv:2606. 30646v1 Announce Type: cross Abstract: Speech recruits the same executive, attentional, and working memory processes underlying instrumental activities of daily living, or IADLs, providing a non-invasive proxy for cognitive assessment.
The paper introduces a contactless, multimodal screening framework that uses video, audio, and text data collected during structured voice interactions with Amazon Alexa to detect mild cognitive impairment (MCI). It evaluates three conversational tasks—spontaneous speech, comprehension, and recall—to determine which provides the most informative signals, compares unimodal models, and assesses multimodal fusion. Results show that while individual modalities perform best on specific tasks, the multimodal model consistently achieves higher accuracy (up to 0.76) across tasks, indicating that integrated behavioral cues can reliably distinguish MCI from healthy aging.
arXiv:2607. 21496v1 Announce Type: cross Abstract: Cognitive impairment (CI) is a growing public health concern.
arXiv:2607. 28687v1 Announce Type: cross Abstract: As populations age, cognitive decline from mild cognitive impairment (MCI) to dementia is a defining health challenge of the coming decades, yet routine assessment often misses its earliest signs.
arXiv:2606. 00345v1 Announce Type: new Abstract: Wearable and mobile sensing technologies enable continuous monitoring of human behavior and health in real-world settings.
arXiv:2607. 10168v1 Announce Type: cross Abstract: It is still hard to find Alzheimer's disease (AD) early, especially when neuroimaging is expensive or tools that depend on language are not available.
Brain4FMs is a unified benchmark for evaluating brain foundation models (BFMs) on both scalp EEG and intracranial EEG (iEEG). It incorporates 17 representative models and 21 public datasets spanning clinical diagnosis, sleep staging, communication, and affective computing, and offers dataset-aware preprocessing, cross‑subject evaluation, and standardized downstream workflows. The benchmark highlights that no single BFM consistently outperforms others across all tasks, modalities, and adaptation protocols, prompting further exploratory analyses of model‑specific spatial, spectral, and discrete representations.
NOAH is a generative transformer that learns the full multimodal patient journey by integrating bidirectional time and a variational latent space. Trained on over 559 million clinical events from 431,000 hospital visits, it processes medical images, time‑series, numeric signals, categorical events, and both structured and unstructured records. The model supports autoregressive forecasting, zero‑shot classification, and counterfactual intervention simulation, yielding strong performance on clinical outcomes, ICD chapters, comorbidities, and time‑to‑event prediction.
arXiv:2606. 28445v1 Announce Type: cross Abstract: Early detection of dementia enables timely intervention, and reflecting cognitive impairment, spontaneous speech offers a non-invasive screening modality.
NOAH is a generative transformer that models the entire multimodal patient journey by integrating bidirectional time and a variational latent space to capture continuous, stochastic clinical trajectories. Trained on over 559 million events from 431,000 hospital visits, it processes medical images, time‑series, numeric signals, categorical events, and both structured and unstructured records. The model supports autoregressive forecasting, zero‑shot classification, and counterfactual simulations, yielding strong predictive performance across 15 ICD chapters, 29 comorbidities, and time‑to‑event outcomes.
The paper presents a diagnostic framework for Alzheimer’s disease that uses the Large Brain Model (LaBraM), a foundation model pretrained on over 2,500 hours of EEG data, to generate high‑dimensional latent embeddings. These embeddings are fed into a non‑linear Random Forest classifier, achieving an ROC‑AUC of 89.36% ± 3.49%, PR AUC of 81.45% ± 4.43%, and Balanced Accuracy of 82.44% ± 4.34% in a subject‑independent 5‑fold cross‑validation setting, using only 8‑second EEG segments. Post‑hoc occlusion and neurophysiological alignment analyses confirm that the model captures clinically validated biomarkers such as occipital‑frontal Alpha and Theta rhythm degradation and correlates with cognitive performance and clinical severity.