arXiv AI

The Greatness of Science Cannot Be Planned: Agentic Auto-Research is Fuzz Testing

The article argues that agentic auto‑research should be guided by dense, intermediate signals of epistemic progress rather than by sparse final benchmarks. It compares this approach to fuzz testing, where coverage provides continuous feedback that directs input mutation. The authors propose controlled experiments to test whether such signals improve discovery efficiency and reduce false positives, and demonstrate in a simulated physics setting that an AI agent using feedback‑driven search uncovers a hidden law while optimization‑driven baselines fail.

arXiv AI
Oct 7

EPOCH: Reliable Discovery through Evidence-Governed Search

EPOCH is an evidence‑governed architecture for AI research agents that improves how candidate discoveries are evaluated and validated. By combining explicit task contracts, typed memory, active falsification, admission checks, and independent replay, EPOCH ensures that each candidate is judged against the strength and scope of its claim. The system achieves state‑of‑the‑art performance on several benchmarks, including AlgoTune, Math14, and AgentHPO, and demonstrates significant advances in executable constructions, algorithm optimization, counterexamples, and proof‑supported results across ten discovery problems.

By Binjie Guo, Aisheng Mo, Ruitong Li, Xinle Deng
arXiv Machine Learning
Sep 23

Recursive self-improvement of AI research agents

The paper introduces AIDE^2, an AI research agent that recursively improves its own code by proposing, benchmarking, and selecting modifications. Over an eight‑day autonomous run, it achieved seven successive improvements—including new search policies and memory mechanisms—that transferred to four held‑out benchmarks in machine learning, algorithm engineering, and weather forecasting. The agent’s best version matched or outperformed a top human‑engineered production research agent and also reduced reward‑hacking rates, despite never optimizing for that metric.

By Dhruv Srikanth, Bingchen Zhao, Dixing Xu, Yuxiang Wu, Zhengyao Jiang
arXiv AI
Jul 14

FIRE-Bench: Evaluating AI Agents on the Rediscovery of Scientific Insights

arXiv:2602. 02905v2 Announce Type: replace Abstract: Autonomous agents powered by large language models (LLMs) promise to accelerate scientific discovery end-to-end, but rigorously evaluating their capacity for verifiable discovery remains a central challenge.

By Zhen Wang, Fan Bai, Zhongyan Luo, Jinyan Su, Kaiser Sun, Xinle Yu, Jieyuan Liu, Kun Zhou, Claire Cardie, Mark Dredze, Zhiting Hu, Eric P. Xing
arXiv AI
Sep 7

La Agente \'Optima: Towards Agentic Self-Driving Laboratories

La Agente ’Optima is an agentic framework that builds and manages Bayesian optimization campaigns for self‑driving laboratories, separating large language model reasoning from campaign execution. It maintains a persistent optimization state, allowing consistent repetitive loops and auditable decisions, and only returns control to the agent when interpretation or revision is needed. In tests on digital discovery tasks and physical platforms, it corrected measurement failures, improved yields, and recommended formulation changes, outperforming human‑directed campaigns in cost and material usage.

By Marcel M\"uller, Jiaru Bai, Willi Gottstein, Abhijoy Mandal, Mohammad Nazeri, Elia Savino, Yanlin Fang, Sujoy Das, Sergio Pablo Garc\'ia Carrillo, Yeonghun Kang, Juan B. P\'erez-S\'anchez, Simone Pilon, Martin Fitzner, Timothy No\"el, Frank Gu, Varinia Bernales, Al\'an Aspuru-Guzik