Neetyabhas: A Framework for Uncertainty-Aware Public Policy Optimization in Rational Agent-Based Models
arXiv:2606. 04562v1 Announce Type: new Abstract: Purpose The WHO's COVID-19 non-pharmaceutical interventions (e.
Purpose The WHO's COVID-19 non-pharmaceutical interventions (e. g.
arXiv:2606. 04562v1 Announce Type: new Abstract: Purpose The WHO's COVID-19 non-pharmaceutical interventions (e.
arXiv:2605. 26704v2 Announce Type: replace-cross Abstract: Epidemic forecasting faces a fundamental challenge: human behavior dynamically responds to disease spread, creating feedback loops that induce distribution shifts at policy intervention points.
arXiv:2607. 08793v1 Announce Type: cross Abstract: Sepsis is a leading cause of mortality, yet optimal treatment policies remain contested.
The paper introduces a signaling‑game framework to model how individuals strategically misreport behavioral data—such as mask usage and vaccination status—to public health authorities. It provides a generative model of such adversarial data and a method for authorities to recover reliable signals, analyzing equilibrium outcomes and evaluating how deception affects epidemic control. Large‑scale simulations and real‑world validation show that well‑designed sender and receiver strategies can still maintain effective epidemic control even with pervasive dishonesty, and that behavioral distortions often follow structured patterns rather than random noise.
arXiv:2606. 05692v1 Announce Type: new Abstract: Deep learning has enabled significant advances in time-series causal inference, yet progress remains constrained by the lack of realistic benchmarks with observable counterfactual outcomes.
arXiv:2607. 16916v1 Announce Type: new Abstract: Bladder cancer treatment requires personalized and adaptive decision-making, particularly for recurrent disease, where treatment effectiveness changes across successive clinical episodes.
Deep learning has enabled significant advances in time-series causal inference, yet progress remains constrained by the lack of realistic benchmarks with observable counterfactual outcomes. Existing datasets either rely on real-world observations without ground-truth counterfactuals or on simplified simulations that fail to capture complex causal dynamics.
The paper presents a study on adaptive chemotherapy control using deep reinforcement learning (DRL) to address tumor heterogeneity and drug resistance. Closed‑loop DRL dosing policies—continuous (TD3) and discrete (DQN)—are trained on a high‑dimensional heterogeneous tumor model and benchmarked against a Pontryagin's Maximum Principle (PMP) open‑loop solution. Across a 100‑patient virtual cohort with ±10% parameter perturbations, TD3 achieves higher average tumor reduction, while DQN offers tighter inter‑patient dosing consistency, highlighting an efficacy‑consistency trade‑off. The work assumes full observation of tumor subpopulations, noting that clinical translation will require handling sparse, noisy measurements.
arXiv:2606. 02867v1 Announce Type: cross Abstract: Human behaviour during epidemics affects infectious disease dynamics, but quantifying this remains deeply challenging.
arXiv:2608. 03606v1 Announce Type: new Abstract: Clinical development is sequential decision-making under uncertainty, where a sponsor must plan a portfolio of experiments from heterogeneous evidence.
arXiv:2508. 03875v2 Announce Type: replace Abstract: Many sequential decision problems offer qualitatively different ways of influencing the environment: some interventions act immediately, whereas others induce persistent effects that continue to shape future states long after the decision that initiated them.
arXiv:2606. 16721v1 Announce Type: new Abstract: Medical diagnosis and treatment are dynamic processes in which patient states evolve over time and clinical interventions alter future outcomes.