Whole-slide image (WSI) diagnosis requires identifying diagnostically relevant regions, examining them across magnifications, and integrating multi-scale evidence. However, most existing pathology benchmarks evaluate models on pre-cropped patches or pre-extracted slide features, leaving their ability to acquire evidence directly from gigapixel WSIs largely untested.
arXiv:2606. 17412v1 Announce Type: cross Abstract: Pathological images are inherently multi-scale, requiring pathologists to integrate evidence from global tissue architecture at low magnification to cellular morphology at higher magnification for accurate diagnosis.
By Chi Phan, Tianyi Zhang, Qiaochu Xue, Yufeng Wu, Dan Hu, Zeyu Liu, Sudong Wang, Yueming Jin
Pathological diagnosis is inherently multi-scale, requiring the integration of global tissue architecture at low magnification with cellular morphology at higher magnification. However, existing pathology benchmarks and vision-language models (VLMs) are still largely developed under single-scale settings, limiting their ability to learn clinically meaningful multi-magnification reasoning.
arXiv:2607. 23794v1 Announce Type: cross Abstract: Pathological diagnosis is inherently multi-scale, requiring the integration of global tissue architecture at low magnification with cellular morphology at higher magnification.
By Chi Phan, Tianyi Zhang, Yufeng Wu, Qiaochu Xue, Jiajie Zhang, Linghan Cai, Zeyu Liu, Sudong Wang, Yueming Jin, Dan Hu
arXiv:2606. 19966v1 Announce Type: cross Abstract: Whole-slide images (WSIs) are widely used for computational cancer prognosis.
By Yucheng Xing, Ling Huang, Pei Liu, Jingying Ma, Jiaqing Xu, Kai He, Mengling Feng
Whole-slide image (WSI) reasoning requires an agent to sequentially acquire visual evidence before answering a diagnostic question. Existing training-free agentic frameworks formulate this process as iterative patch retrieval based on semantic relevance to the question.
arXiv:2605. 30716v2 Announce Type: replace-cross Abstract: Generating clinically useful pathology reports for pathology cases from whole-slide images (WSIs) is challenging due to gigapixel resolution, long visual-token sequences, and the complexity of case-level reasoning, where a single case may contain multiple WSIs with heterogeneous tissues and ambiguous findings.
By Zhiyuan Yang, Jiahao Cheng, Vincent Quoc-Huy Trinh, Mahdi S. Hosseini
arXiv:2607. 12278v1 Announce Type: cross Abstract: Recent vision-language models (VLMs) for computational pathology report striking zero-shot performance on whole-slide image (WSI) visual question answering (VQA) benchmarks.
By Wenhao Zhang, Zhongliang Zhou, John Kang, Sheng Li
Current evaluation protocols for Vision-Language Models (VLMs) in Radiology Report Generation (RRG) rely on report-level metrics that measure lexical overlap or aggregate clinical correctness. However, such metrics do not test whether individual diagnostic statements stem from the actual pathological evidence visible in the image.
Pathology vision-language models (VLMs) have recently progressed rapidly and are commonly evaluated by answer accuracy on pathology VQA benchmarks. However, we dig into current evaluations and identify three overlooked issues: 1) Visual evidence is not always necessary.
arXiv:2608. 10827v1 Announce Type: cross Abstract: Medical visual agents can use tools to inspect images and retrieve external knowledge, but indiscriminate tool use may introduce noisy or misleading evidence.
By Shengzhi Wang, Jun Yang, Kai Wu, Xiaozhong Ji, Yiwen Ye, Ziyang Chen, Mingliang Xiong, Wen Fang, Mingqing Liu, Mengyuan Xu, Miaoxuan Shan, Caiyan Liu, Bin He, Qingwen Liu
arXiv:2511. 18676v2 Announce Type: replace-cross Abstract: Current vision-language models (VLMs) in medicine are primarily designed for categorical question answering (e.
By Yongcheng Yao, Yongshuo Zong, Raman Dutt, Yongxin Yang, Sotirios A Tsaftaris, Timothy Hospedales