arXiv AI

Structured Affinity for Unsupervised Visual Class-Incremental Memory in Deep Artificial Immune Networks

arXiv:2608. 20104v1 Announce Type: cross Abstract: Artificial immune networks (AINs) are naturally memory-forming systems, but conventional visual AINs often rely on flattened vector affinity that ignores spatial structure.

arXiv AI
Jul 23

SubQuad: Near-Quadratic-Free Structure Inference with Distribution-Balanced Objectives in Adaptive Receptor framework

arXiv:2602. 17330v5 Announce Type: replace-cross Abstract: Comparative analysis of adaptive immune repertoires at population scale is hampered by two practical bottlenecks: the near-quadratic cost of pairwise affinity evaluations and dataset imbalances that obscure clinically important minority clonotypes.

By Rong Fu, Zijian Zhang, Kun Liu, Jiekai Wu, Xianda Li, Simon Fong
arXiv Machine Learning
Aug 12

AgForce Enables Antigen-conditioned Generative Antibody Design

arXiv:2605. 21610v2 Announce Type: replace Abstract: Antibody design methods condition on antigen structure to generate complementarity-determining regions (CDR), yet a systematic evaluation of baseline methods reveals that they largely ignore the antigen input.

By Mansoor Ahmed, Murray Patterson
arXiv AI
Jun 18

Clin-JEPA: A Multi-Phase Co-Training Framework for Joint-Embedding Predictive Pretraining on EHR Patient Trajectories

arXiv:2605. 10840v3 Announce Type: replace-cross Abstract: We present Clin-JEPA, a multi-phase co-training framework for joint-embedding predictive (JEPA) pretraining on EHR patient trajectories.

By Yixuan Yang, Mehak Arora, Ryan Zhang, Baraa Abed, Junseob Kim, Tilendra Choudhary, Md Hassanuzzaman, Kevin Zhu, Ayman Ali, Chengkun Yang, Alasdair Edward Gent, Victor Moas, Rishikesan Kamaleswaran
arXiv Machine Learning
Jul 23

SwiftRepertoire: Few-Shot Immune-Signature Synthesis via Dynamic Kernel Codes

arXiv:2602. 01051v5 Announce Type: replace Abstract: Repertoire-level analysis of T cell receptors offers a biologically grounded signal for disease detection and immune monitoring, yet practical deployment is impeded by label sparsity, cohort heterogeneity, and the computational burden of adapting large encoders to new tasks.

By Rong Fu, Muge Qi, Yang Li, Yabin Jin, Jiekai Wu, Chunlei Meng, Juntao Gao, Li Bao, Qi Zhao, Wei Luo, Youjin Wang, Simon Fong
arXiv AI
Jul 22

Soft-TransFormers for Continual Learning

arXiv:2411. 16073v4 Announce Type: replace-cross Abstract: Inspired by the Well-initialized Lottery Ticket Hypothesis (WLTH), we introduce Soft-TransFormers (Soft-TF), a continual learning framework that adapts a frozen pre-trained Transformer through task-specific soft subnetworks: real-valued multiplicative masks over the query, key, value, and output projections of selected self-attention layers.

By Haeyong Kang, Chang D. Yoo
arXiv Computer Vision
Aug 31

Activation Boundary Matching: Task-Informed Initialization for Low-Rank Adaptation

The paper introduces Activation Boundary Matching for Low‑Rank Adaptation (ABM‑LoRA), a task‑informed initialization strategy that uses the signs of layer‑wise pre‑activations from a brief probe adapter as targets for a fresh adapter. By training with a margin‑based hinge objective on these activation boundaries, ABM‑LoRA captures useful adaptation directions that standard LoRA initializers miss, while requiring only a few forward passes. Experiments show that ABM‑LoRA outperforms or matches existing LoRA, SVD, and gradient‑based initializers across multiple models and benchmarks, including T5‑base/GLUE, ConvNeXt‑T, Swin‑T, Qwen2.5‑1.5B, and LLaMA2‑7B.

By Dongha Lee, Jinhee Park, Minjun Kim, Junseok Kwon