LiteMedCoT-VL is a parameter‑efficient pipeline that transfers chain‑of‑thought reasoning from a 235B teacher model to a 2B student model using LoRA fine‑tuning on explanation‑enriched data. The approach enables a compact vision‑language model to perform medical visual question answering without relying on image captions, achieving 64.9% accuracy on the PMC‑VQA benchmark—an 11‑point improvement over the zero‑shot Qwen3‑VL‑4B baseline. Visual grounding analysis confirms that the model bases its predictions on image content rather than textual priors.
By Runze Ma, Shunbo Jia, Haonan Lyu, Guo Liu, Caizhi Liao
arXiv:2606. 12169v1 Announce Type: cross Abstract: High-stakes clinical use of large vision-language models (LVLMs) requires reasoning that is grounded in visual evidence and clinical knowledge, not just correct final answers.
By Negin Baghbanzadeh, Pritam Sarkar, Michael Colacci, Abeer Badawi, Adibvafa Fallahpour, Arash Afkanpour, Leonid Sigal, Ali Etemad, Elham Dolatabadi
arXiv:2605. 18419v2 Announce Type: replace-cross Abstract: Vision-language models (VLMs) can couple visual perception with open-ended clinical reasoning, making them attractive for computational histopathology.
By Franciskus Xaverius Erick, Johanna Paula M\"uller, Bernhard Kainz
The paper introduces ThoughtMed-1M, a large-scale medical visual question answering dataset built from de‑identified images and clinician‑generated commentaries, designed to capture structured clinical reasoning and image‑text alignment. Using this dataset, the authors train FOLTMed, a foundational large language model that achieves state‑of‑the‑art performance on 42 medical VQA benchmarks, with a macro accuracy of 85.4% and improved factuality and similarity metrics over existing models.
By Lingxuan Hou, Yuhua Xie, Yue Hu, Yan Zhuang, Junqi Li, Chengzhi Xia, Binh Phu Nguyen, Abubakar Siddique, Minh Nguyen, Yao Hou, Yanju Bao, Kexin Liu, Ke Chen, Jianjun Sun, Zeqi Li, Trung Nguyen, Jiangli Lin
arXiv:2509.22404v2 Announce Type: replace
Abstract: Anatomical understanding, which is the ability to identify, localize, or segment anatomical structures, is critical in medical image analysis; howe...
By Yiwei Li, Yikang Liu, Jiaqi Guo, Lin Zhao, Zheyuan Zhang, Xiao Chen, Boris Mailhe, Ankush Mukherjee, Terrence Chen, Shanhui Sun
arXiv:2609.32352v2 Announce Type: replace-cross
Abstract: Vision-language models (VLMs) have shown increasing potential for medical image understanding, yet their capabilities in ophthalmic imaging r...
By Gujie Shao, Zixun Xie, Xuechun Xing, Ruixiang Wang, Ziyun Lan, Yanlin Qi, Gangyi Zhang, Yuxin Yang, Dawei Li, Haiming Tang
MultiViewDx is a physician‑validated multimodal instruction dataset that links medical imaging studies with patient context and normalizes heterogeneous reports into an evidence‑linked workflow (evidence → findings → differential discussion → diagnosis). The dataset covers a wide range of imaging modalities and uses a unified image‑text retriever to ensure that instruction synthesis is grounded in source‑supported evidence. Fine‑tuned models on MultiViewDx achieve the highest average accuracy on four MedVQA benchmarks and receive the strongest overall rating on JAMA Clinical Challenge cases, with ablations confirming the importance of case‑level multi‑view organization and evidence‑linked reasoning.
By Junda Wang, Zonghai Yao, Yujan Ting, Eric Z. Chen, Hieu Tran, Hong Yu, Weijing Huang, Terrence Chen
MedGEN-Bench is a new benchmark for open‑ended multimodal medical generation that addresses limitations in current medical visual benchmarks, such as query‑image misalignment, closed‑ended answer spaces, and text‑centric outputs. The dataset contains 6,422 image‑text pairs across six imaging modalities, 15 clinical tasks, and 27 subtasks, including VQA, image editing, and contextual multimodal generation pairs. Evaluation combines reference‑based fidelity metrics with a structured, checklist‑guided assessment by a medical VLM judge, and preliminary results show that image‑output tasks remain unsaturated while contextual augmentation improves image‑instruction similarity.
By Junjie Yang, Yuhao Yan, Gang Wu, Rui Qian, Zhisheng Chen, Haijiang Li, Yuhe Wu, Qichao Zhao, Dawen Tian, Xiang Wan, Fenglei Fan, Wenjian Qin, Yongquan Zhang, Feiwei Qin, Changmiao Wang
arXiv:2606. 28556v1 Announce Type: new Abstract: Recent advances in large language models and vision-language models have enabled reasoning over multimodal data, offering opportunities for clinical applications such as decision support and triaging.
By Maria Xenochristou, Ashutosh Joshi, Korosh Vatanparvar, Mohammad Abuzar Hashemi, Prasad Kasu, Deepak Bansal, Anchal Nema, Nivedita Wadhwa, Prashams S Jain, Rebecca Abraham, Will Kimbrough, Dilek Hakkani-Tur, Wilko Schulz-Mahlendorf
arXiv:2608. 15580v1 Announce Type: new Abstract: Reliable endoscopic polyp reporting requires integrating quantitative lesion sizing, standardized Paris classification, and clinically meaningful morphological description within a single record.
By Ruijie Yang, Yan Zhu, Peiyao Fu, Siyuan Li, Te Luo, Zhihua Wang, Quanlin Li, Pinghong Zhou, Xian Yang, Shuo Wang
arXiv:2609.37283v1 Announce Type: new
Abstract: Medical multimodal large language models (MLLMs) are increasingly expected not only to answer clinical questions, but also to localize the visual evide...
By Xuyang Cao, Enyou Liu, Jun Zhao, Zhuoyun Liu, Jintao Fei, Leo
The paper introduces MedREAL, a unified framework that aligns linguistic reasoning with spatial grounding for medical visual question answering and segmentation. MedREAL employs Seg Anchored Reasoning Pooling (SARP) to extract semantic evidence from segmentation tokens and a Reasoning-to-Visual (R2V) fusion mechanism to integrate these features into a segmentation pipeline. Using the newly created MedRAVS-13K dataset, MedREAL achieves superior performance, reporting 68.49% gIoU and 70.47% cIoU, and generates evidence masks that consistently match textual diagnoses.
By Haowen Gu, Gensheng Pei, Junzhu Mao, Qiong Wang, Mingwu Ren, Yazhou Yao