arXiv:2511.12041v4 Announce Type: replace-cross
Abstract: Super-resolution flow reconstruction using state-of-the-art data-driven techniques is valuable for a variety of applications, such as subgrid...
By Shivam Barwey, Pinaki Pal
The paper introduces TI$^2$PS, a topology-informed inverse design framework that estimates agent-based model parameters to reproduce target multicellular patterns. It combines Betti vectors from topological data analysis with inverse surrogate modeling to address challenges in parameter estimation and topological evaluation under stochastic cell dynamics. Validation on zebrafish pigment pattern formation shows the framework outperforms conventional methods, achieving superior results with only 10% of the training data.
By Kenji Komiya, Andrew Kailiang Jin, Ryo Nishikimi, Kunio Kashino
arXiv:2608.27883v1 Announce Type: new
Abstract: Physical systems are often modeled by solution operators that map input fields, parameters, geometries, or past states to steady or future physical sta...
By Rajat Sarkar, Venkataramana Runkana, Souvik Chakraborty
arXiv:2606. 10255v1 Announce Type: cross Abstract: Cryo-electron tomography (cryoET) has emerged as a powerful tool in structural and cellular biology by enabling direct visualization of macromolecular structures within intact cells, thereby linking molecular architecture to cellular organization in a native context.
By Jonathan Schwartz, Utz Heinrich Ermel, C. Braxton Owens, Zhuowen Zhao, Ariana Peck, Gus L. W. Hart, Grant J. Jensen, Bridget Carragher, Dari Kimanius
The paper introduces an end‑to‑end framework for detecting and classifying cells in pathology images by jointly modeling visual features and instance‑level interactions. It employs a dynamic graph construction module that builds cell graphs from learnable queries and an instance‑aware graph network that filters and reorganizes features, integrating appearance and relational evidence. Experiments on multiple staining protocols show the method surpasses existing approaches in both detection and classification accuracy.
By Ruochen Liu, Yalin Zheng, Jingxin Liu, Jianfeng Zhang, Shoujun Huang, Dexing Kong, Haofeng Li, Wei Lou
LapDDPM is a conditional Graph Diffusion Probabilistic Model that generates high‑fidelity, biologically plausible single‑cell RNA sequencing data. It incorporates graph‑based inductive biases and a spectral adversarial perturbation mechanism to enforce robustness against structural noise, effectively acting as a Distributionally Robust Optimization framework. The model extends to spatial transcriptomics and multi‑modal data, and experimental results on datasets such as PBMC3K, Dentate Gyrus, HLCA, Visium, and 10x Multiome show it outperforms state‑of‑the‑art baselines in distribution matching, manifold preservation, and downstream utility.
By Lorenzo Bini, Stephane Marchand-Maillet
arXiv:2512. 18454v3 Announce Type: replace Abstract: Predictive machine learning models generally excel on in-distribution data, but their performance degrades on out-of-distribution (OOD) inputs.
By David Graber, Victor Armegioiu, Rebecca Buller, Siddhartha Mishra
arXiv:2608. 07575v1 Announce Type: cross Abstract: Confocal microscopy of optically cleared and swelled tissue resolves complex biological structures in 3D, but such acquisitions are highly anisotropic: along the under-sampled axial direction the structure can appear discontinuous, hampering reconstruction and automated quantitative analysis.
By Arash Fatehi, Robin Ebbestad, Linus Butt, Hans Blom, Sigrid Lundberg, Hannes Olauson, Hjalmar Brismar, David Unnersj\"o-Jess, Thomas Benzing, Katarzyna Bozek
arXiv:2608. 14058v1 Announce Type: cross Abstract: Seismic facies segmentation has emerged as a significant challenge in geophysics, requiring robust methods and systems to effectively identify geologically analogous facies with limited labeled data.
By Duc-Thanh Pham, Minh-Tan Pham, Anh Nguyen, Van Nguyen
arXiv:2606. 08258v1 Announce Type: cross Abstract: Understanding and comparing structures in scalar fields is a central challenge in scientific visualization, with applications ranging from feature analysis to temporal and structural comparison.
By Guangyu Meng, Mingzhe Li, Erin Wolf Chambers
The paper introduces a differentiable voxelization technique that computes gradients of volumetric properties, such as winding numbers, with respect to surface mesh parameters. This method allows efficient optimization of triangle meshes using voxel-based volume samples on a regular grid. The authors demonstrate its utility in applications like resolving mesh intersections, designing manufacturable shapes for bandsaw cutting, and creating near-tiling 3D structures.
By Tobias Djuren, Ugo Finnendahl, Markus Worchel, Hendrik Meyer, Marc Alexa
arXiv:2607. 02564v1 Announce Type: cross Abstract: Computational models of the human heart are widely used to study electromechanical and fluid-dynamical cardiac function and to support applications such as in silico clinical trials.
By Francesco Fabbri, Martino Andrea Scarpolini, Paolo Ciancarella, Francesco Tudisco, Roberto Verzicco, Alessandro Ricci, Francesco Viola