This scoping review examined 48 studies on generative AI chatbots designed to deliver motivational interviewing (MI). It found that most systems were text‑based and disembodied, with about half incorporating dynamic adaptation, and that safety reporting was inconsistent. While user perceptions were generally positive and many studies reported MI‑consistent interactions, evidence for sustained behavioral or functional change remains limited.
By Runze Hu, Jingqi Kong, Yang Yang, Yihang Yang, Jingyao Liu, Haizhou Tang, Shanghang Zhang, Zheng Liu
arXiv:2606. 17474v1 Announce Type: cross Abstract: Large language models (LLMs) are increasingly considered for use in clinical consultation tasks, yet most medical evaluations remain static, single-turn, or narrowly outcome-based, limiting their ability to reflect the sequential, uncertain, and interactive nature of real-world care.
By Jiahui Niu, Huizi Yu, Wenkong Wang, Guangxin Dai, Jingxian He, Xiang Li, Zhiying Liang, Xinxin Lin, Kent CY So, Bryan YP Yan, Yun Kwok Wing, Yanqiu Xing, Xin Ma, Lizhou Fan
arXiv:2604.25415v2 Announce Type: replace-cross
Abstract: People increasingly turn to general-purpose AI chatbots for advice about emotional and mental health problems, but the ability of these syste...
By Veith Weilnhammer, Lennart Luettgau, Christopher Summerfield, Raymond Dolan, Elise Wilkinson, Virginia Corno, Viknesh Sounderajah, Matthew M Nour
arXiv:2607. 09253v1 Announce Type: cross Abstract: AI chatbots are increasingly used for answering health-related questions.
By Gwenn Beets, Anniek Jansen, Saar Hommes, Ruben D. Vromans, Leonie Westerbeek, Supraja Sankaran, Julia C. M. van Weert, Emiel J. Krahmer, Nadine Bol
arXiv:2603.18008v2 Announce Type: replace-cross
Abstract: Large language models (LLMs) are increasingly used for mental-health support; yet prevailing evaluation methods--fluency metrics, preference...
By Fangrui Huang, Souhad Chbeir, Arpandeep Khatua, Sheng Wang, Sijun Tan, Kenan Ye, Lily Bailey, Merryn Daniel, Ryan Louie, Sanmi Koyejo, Ehsan Adeli
arXiv:2509. 02594v3 Announce Type: replace-cross Abstract: Evaluating large language models (LLMs) on their ability to generate high-quality, accurate, situationally aware answers to clinical questions requires going beyond conventional benchmarks to assess how these systems behave in complex, high-stakes clinical scenarios.
By Sandhanakrishnan Ravichandran, Shivesh Kumar, Rogerio Corga Da Silva, Miguel Romano, Reinhard Berkels, Michiel van der Heijden, Olivier Fail, Valentine Emmanuel Gnanapragasam
arXiv:2605. 18937v2 Announce Type: replace Abstract: Patient-managed Personal Health Records (PHRs) promises to empower patients to better understand their health; but information in the record is complex, potentially hindering insights.
By Rory Sayres, Kejia Chen, Ayush Jain, Matthew Thompson, Jonathan Richina, Xiang Yin, Jimmy Hu, Fan Zhang, Bob Lou, Mike Sanchez, Ines Mezerreg, Meredith Schreier, Hamsa Subramaniam, I-Ching Lee, Yugang Jia, Daniel Mcduff, Yossi Matias, Avinatan Hassidim, Dale Webster, Yun Liu, Jackie Barr, Quang Duong
SIM-UT is a multi‑turn, user‑simulation evaluation framework designed to uncover realistic failure modes in large‑language‑model (LLM) medical triage chatbots. The study applied SIM‑UT to three WhatsApp‑based health chatbots in India, South Africa, and Kenya, comparing a medically fine‑tuned model (MedGemma) with general‑purpose models (ChatGPT and Claude) across more than 5,000 multilingual simulated conversations. A prominent failure identified was de‑escalation risk, where chatbots incorrectly down‑rated serious symptoms after users minimized them, potentially leading to dangerous clinical outcomes.
By Deepali Mittal, Dheeraj Mundhra, Yulia Sidorova, Tersia de Kock, Oli Munns, Sofie S Meyer
The study examined how clinicians and GPT‑4 evaluate emergency department revisit pairs to determine if further assessment is needed. GPT‑4 over‑identified nearly all pairs as requiring follow‑up, while clinicians used clinical gravity and differential diagnosis factors. An algorithm using a knowledge graph populated by an LLM achieved high positive predictive value for identifying pairs that clinicians deemed warranting review.
By Jonathan A. Handler, Marlene I. Robles-Granda, Jacob E. Mefford, Jeremy S. McGarvey, Gregory S. Podolej, Colleen J. Klein, Matthew D. Dalstrom, William F. Bond
arXiv:2602. 05088v4 Announce Type: replace Abstract: Millions of people now use generative AI chatbots for psychological support.
By Kate H. Bentley, Luca Belli, Adam M. Chekroud, Emily J. Ward, Emily R. Dworkin, Emily Van Ark, Kelly M. Johnston, Will Alexander, Millard Brown, Matt Hawrilenko
arXiv:2512. 01241v4 Announce Type: replace-cross Abstract: Large language models (LLMs) and medical AI tools are routinely used by physicians and patients for medical advice, yet their clinical safety profiles remain poorly characterized.
By David Wu, Fateme Nateghi Haredasht, Saloni Kumar Maharaj, Priyank Jain, Jessica Tran, Matthew Gwiazdon, Arjun Rustagi, Jenelle Jindal, Jacob M. Koshy, Vinay Kadiyala, Anup Agarwal, Bassman Tappuni, Brianna French, Sirus Jesudasen, Christopher V. Cosgriff, Rebanta Chakraborty, Jillian Caldwell, Susan Ziolkowski, David J. Iberri, Robert Diep, Rahul S. Dalal, Kira L. Newman, Kristin Galetta, J. Carl Pallais, Nancy Wei, Kathleen M. Buchheit, David I. Hong, Vartan Pahalyants, Ernest Y. Lee, Allen Shih, Tamara B. Kaplan, Vishnu Ravi, Sarita Khemani, Thomas A. Buckley, April S. Liang, Daniel Shirvani, Advait Patil, Nicholas Marshall, Kanav Chopra, Joel Koh, Adi Badhwar, Anastasia Perez, Austin J. Schoeffler, Mahbuba Tusty, Chase M. Walton, Liam G. McCoy, David J. H. Wu, Yingjie Weng, Sumant Ranji, Kevin Schulman, Nigam H. Shah, Jason Hom, Arnold Milstein, Arjun K. Manrai, Adam Rodman, Jonathan H. Chen, Ethan Goh
arXiv:2607. 24817v1 Announce Type: cross Abstract: Digital mental health interventions (DMHIs) offer scalable support, but ensuring they accurately detect users' intent during volatile situations can be challenging.
By Anand Gupta, Akshat Surolia, Shubham Mishra, Shakil Imtiaz, Chaitali Sinha