arXiv Machine Learning

Unsupervised Anatomical Feature Learning via Diffusion Models: Enhanced Medical Image Segmentation with Denoising Diffusion Probabilistic Models

The paper introduces an unsupervised approach to medical image segmentation by training a Denoising Diffusion Probabilistic Model (DDPM) on 21 unlabeled abdominal CT scans to learn anatomical features. The encoder weights from the DDPM are transferred to a U‑Net for downstream segmentation on the BTCV multi‑organ dataset, resulting in a significant Dice score improvement for liver segmentation from 0.75 to 0.93. In low‑data regimes, diffusion‑pretrained models retain robust performance, achieving high Dice scores even with only 10% of labeled data.

arXiv Machine Learning
Aug 5

Assessment of Conditional Diffusion Model for Synthetic Histopathology Image Generation

arXiv:2608. 03990v1 Announce Type: new Abstract: Synthetic histopathology image generation has emerged as an approach that may address data scarcity in computational pathology, yet current evaluation methodologies may not fully assess synthetic data quality for medical applications.

By Seyed Kahaki, Shijie Li, Weijie Chen, Nicholas Petrick
arXiv Machine Learning
Jun 18

Structural MRI Synthesis for Alzheimer's Disease via Conditional Diffusion on Anatomical Masks

arXiv:2606. 18354v1 Announce Type: cross Abstract: Recent advances in generative machine learning models have significantly improved medical imaging, offering promising solutions for data augmentation, privacy preservation, and improved model generalization.

By Muge Zhang, Muhammad Ali Khaliq, Jamal Alsakran, Byeong Kil Lee, Jeeho Ryoo
arXiv Computer Vision
4d ago

DALE-CT: Depth-Aware 2D Slice Encoders Learn an Anatomical World Model of Chest CT

DALE-CT introduces depth‑aware 2D slice encoders that learn an anatomical world model of chest CT scans without 3D or positional supervision. By sampling self‑supervised views across a physical $z$‑axis slab, the encoder captures how anatomy changes between neighboring slices, enabling it to recover slice ordering and distinguish slices by anatomy alone. The model, trained on a large 287k‑scan corpus, achieves state‑of‑the‑art performance on CT‑RATE and is released with full code and evaluation tools.

By Evan W. Damron, Mahmut S. Gokmen, Mitchell A. Klusty, Caroline N. Leach, Emily B. Collier, V. K. Cody Bumgardner
arXiv AI
Aug 25

SAS: Segment Anything Small for Ultrasound -- A Non-Generative Data Augmentation Technique for Robust Deep Learning in Ultrasound Imaging

The paper introduces Segment Anything Small (SAS), a data‑augmentation method that improves deep‑learning segmentation of small anatomical structures in ultrasound images. SAS uses two transformations: resizing and embedding organ thumbnails into a black background to vary organ scale, and adding noise to regions of interest to mimic tissue texture variability. Experiments on one internal and five external datasets show Dice score gains up to 0.35, with an average improvement of 0.16, and demonstrate that SAS enhances model robustness and generalizability without adding hallucinations or artifacts.

By Danielle L. Ferreira, Ahana Gangopadhyay, Hsi-Ming Chang, Ravi Soni, Gopal Avinash
arXiv Machine Learning
Aug 3

Leveraging Transfer Learning with Class-Specific Decoders for Laparoscopic Segmentation

arXiv:2607. 29509v1 Announce Type: cross Abstract: Effective multi-organ segmentation in surgical data requires learning the intricate anatomical features and alleviating the challenge of class imbalance, which results from relatively lower proportions of small and limitedly exposed structures.

By Priya Tomar, Aditya Parikh, Christian Bauckhage, Rafet Sifa