arXiv AI

An interpretable and trustworthy AI framework for large-scale longitudinal structure-pain association studies using data from the Osteoarthritis Initiative (OAI)

arXiv:2606. 05357v1 Announce Type: new Abstract: Purpose: To develop an interpretable and trustworthy AI framework that combines deep learning based MRI Osteoarthritis Knee Score (MOAKS) prediction with interpretable statistical modeling to study structure-pain relationships at scale using data from the Osteoarthritis Initiative (OAI).

arXiv AI
Aug 18

PLeDO: Pain Level Detection for Osteoarthritis from EMR Data

arXiv:2608. 15719v1 Announce Type: new Abstract: Osteoarthritis (OA) is a progressive chronic joint disease resulting in a breakdown of articular cartilage and bone when damaged joint tissues are not able to normally repair themselves.

By Yuhao Chen, Jiahao Cai, Nafiz Sadman, Farhana Zulkernine, John Queenan, David Barber
arXiv Computer Vision
Sep 10

SA-Profile: Automated Sulcus Angle Profiling from Super-Resolution MRI

arXiv:2609.10125v1 Announce Type: new Abstract: Trochlear dysplasia (TD) is an abnormality of the femoral trochlea associated with anterior knee pain and patellar instability. The sulcus angle (SA) i...

By Michael Wehrli, Leo Widmer, Edwin Li, Noel Fiechter, Lorenzo Pettinari, Sidaty El Hadramy, Carol C. Hasler, Philippe C. Cattin
arXiv Machine Learning
Jul 21

Differentiable latent structure discovery for interpretable forecasting in clinical time series

arXiv:2604. 27967v2 Announce Type: replace Abstract: Background: We introduce StructGP, a continuous-time multi-task Gaussian process that couples process convolutions with differentiable structure learning to uncover a sparse, ordered directed acyclic graph (DAG) of inter-variable dependencies while preserving principled uncertainty.

By Ivan Lerner, Jean Feydy, Alexandre Kalimouttou, Anita Burgun, Francis Bach
arXiv Computer Vision
Sep 23

Neoadjuvant chemotherapy response prediction using pretreatment diffusion and contrast-enhanced magnetic resonance imaging with clinical variables

arXiv:2609.26105v1 Announce Type: cross Abstract: Prediction of pathological complete response before neoadjuvant chemotherapy may facilitate more tailored therapeutic planning for breast cancer pati...

By Pablo Garc\'ia Marcos, Paula Puerta Gonz\'alez, Guillermo Lorenzo, H\'ector G\'omez, Covadonga del Camino, Ad\'an Rodr\'iguez, Ignacio Pel\'aez, Angel Rio-Alvarez, V\'ictor M. Gonz\'alez
arXiv AI
Jun 17

Probing, Fusion, and Trustworthiness: A Systematic Evaluation of Foundation Model Representations for Multimodal Cancer Analysis

arXiv:2606. 17115v1 Announce Type: cross Abstract: Foundation models (FMs) have emerged as powerful representation extractors for medical data, yet their generalizability to datasets under distribution shift remains underexplored.

By Jingyu Hu, Giuseppe Tripodi, Reed Naidoo, Sarah F. McGough, Tapabrata Chakraborti
arXiv AI
Aug 10

Measurements Automatically Extracted from Zero Echo Time MRI Using Deep Learning Image Segmentation and Geometric Modeling Agree with Expert Manual Readings

arXiv:2608. 07368v1 Announce Type: cross Abstract: Computed tomography (CT) remains the reference for 3D osseous morphometry in femoroacetabular impingement (FAI) but requires ionizing radiation and manual measurement.

By Jack Consolini, Eric A. Bogner, Meghan Sahr, Matthew F. Koff, Kevin M. Koch, Hollis G. Potter
arXiv Machine Learning
Aug 28

Quantitative mapping from conventional MRI using self-supervised physics-guided deep learning: applications to a large-scale, clinically heterogeneous dataset

This study introduces a self‑supervised, physics‑guided deep‑learning framework that converts standard clinical T1‑, T2‑, and FLAIR MRIs into quantitative T1, T2, and proton‑density maps. Trained on 4,121 scan sessions from four different 3 T scanners over six years, the method produces maps whose white‑ and gray‑matter values fall within literature ranges and shows minimal variation across scanner hardware and acquisition protocols (coefficients of variation ≤ 1.1 %). Voxel‑wise reproducibility is high, with Pearson and concordance correlation coefficients above 0.82 for T1 and T2 and mean relative differences below 6 % for T2.

By Jelmer van Lune, Stefano Mandija, Oscar van der Heide, Matteo Maspero, Martin B. Schilder, Jan Willem Dankbaar, Cornelis A. T. van den Berg, Alessandro Sbrizzi