The paper introduces an unsupervised approach to medical image segmentation by training a Denoising Diffusion Probabilistic Model (DDPM) on 21 unlabeled abdominal CT scans to learn anatomical features. The encoder weights from the DDPM are transferred to a U‑Net for downstream segmentation on the BTCV multi‑organ dataset, resulting in a significant Dice score improvement for liver segmentation from 0.75 to 0.93. In low‑data regimes, diffusion‑pretrained models retain robust performance, achieving high Dice scores even with only 10% of labeled data.
By Akshat G, Divyansh Gupta, Shaleen Bhatnagar, Shilpa Ankalaki, Tusar Kanti Mishra
Acquiring pixel-level annotations for medical image segmentation is a severe bottleneck. Traditional U-Net architectures, while effective, learn local texture patterns and lack awareness of global ana...
arXiv:2602.20773v2 Announce Type: replace
Abstract: Purpose: Developing generalizable medical image segmentation models is challenging because imaging data are distributed across institutions and dif...
By Sachin Dudda Nagaraju, Ashkan Moradi, Bendik Skarre Abrahamsen, Mattijs Elschot
The paper introduces S$^3$F-Net, a dual‑branch network that fuses spatial and spectral representations for medical image classification. It combines a deep spatial CNN with a shallow spectral encoder, SpectraNet, which uses a learnable SpectralFilter layer to process the full Fourier spectrum efficiently. Evaluated on four medical imaging datasets, S$^3$F-Net consistently outperforms spatial‑only baselines, achieving state‑of‑the‑art accuracy on BRISC2025 and surpassing deeper models on the Chest X‑Ray Pneumonia dataset.
By Md. Saiful Bari Siddiqui, Mohammed Imamul Hassan Bhuiyan
arXiv:2607. 02185v1 Announce Type: cross Abstract: Deep learning has achieved remarkable performance in medical image segmentation, yet it suffers from critical limitations: mathematical intractability, substantial parameter requirements, and lack of clinical interpretability.
By Mohammad Amanour Rahman
The study evaluates four deep‑learning segmentation architectures—Unet, PSPNet, Linknet, and FPN—paired with six pre‑trained encoders to predict COVID‑19 lesions in CT images. Experiments on three COVID‑19 CT datasets show high accuracy, achieving a maximum binary F1‑score of 98% and multi‑class F1‑scores of 75% and 77%. The work aims to provide a standardized performance benchmark for medical image segmentation and a reference for other imaging scenarios.
By Sarmad Khan, Basim Azam, Arslan Shaukat
arXiv:2608.23745v1 Announce Type: cross
Abstract: Accurate brain tumor segmentation from magnetic resonance imaging (MRI) is essential for diagnosis, treatment planning, surgical guidance, and diseas...
By Mohammad Mahdi Danesh Pajouh, Sara Saeedi
arXiv:2509.25549v3 Announce Type: replace-cross
Abstract: Choroidal nevi are common benign pigmented lesions in the eye, with a small risk of transforming into melanoma. Early detection is critical t...
By Mohammadmahdi Eshragh, Emad A. Mohammed, Behrouz Far, Ezekiel Weis, Carol L Shields, Sandor R Ferenczy, Trafford Crump
arXiv:2608. 15537v1 Announce Type: cross Abstract: Accurate boundary delineation remains a persistent challenge in dermoscopic image segmentation because of blurred lesion margins, heterogeneous textures, and complex background artifacts.
By Wang Jiangtao, Nur Intan Raihana Ruhaiyem, Fu Panpan, Yang Yu, Huang Yan
The paper introduces a Deep Active Contour and Mean Curvature (DACMC) loss function for medical image segmentation. By incorporating mean curvature as a geometric constraint and approximating it with a convolution kernel, the method aims to improve the geometric characterization of segmented regions. Experiments on liver and spleen datasets show that DACMC achieves new state‑of‑the‑art performance across several segmentation benchmarks.
By Xiao-qiang Zhai, Zhi-feng Pang, Peng Zheng, Ze-wen Li, Yan-zhe Hou
arXiv:2606. 07633v1 Announce Type: cross Abstract: Accurate classification of nuclei subtypes in histopathology images is critical for downstream tasks including tumor grading, immune infiltrate quantification, and prognosis prediction.
By Spoorthi M, Suja Palaniswamy
Brain tissue microstructure estimation with machine learning provides higher computational efficiency than conventional fitting. However, machine learning still presents important limitations that hamper its clinical utility.