arXiv AI

MedMemoryBench: Benchmarking Agent Memory in Personalized Healthcare

MedMemoryBench is a new benchmark designed to evaluate memory mechanisms in personalized healthcare agents, addressing the shortcomings of existing open‑domain conversation benchmarks. It uses a human‑agent collaborative pipeline to generate realistic, long‑horizon medical trajectories from synthetic patient archetypes, producing a dataset of roughly 2,000 sessions and 16,000 interaction turns. The benchmark introduces an "evaluate‑while‑constructing" streaming assessment protocol that mirrors dynamic memory accumulation in production, and it formally studies memory saturation—how continuous information influx can degrade retrieval and reasoning. The results highlight significant bottlenecks in current architectures, especially in complex medical reasoning and noise resilience, underscoring the need for more robust, production‑ready medical agents.

arXiv AI
Jul 1

HealthAgentBench: A Unified Benchmark Suite of Realistic Agentic Healthcare Environments for Challenging Frontier AI Agents

arXiv:2606. 31179v1 Announce Type: new Abstract: As AI agents become increasingly capable of complex, long-horizon reasoning, rigorous and holistic evaluation is essential for measuring progress toward real-world healthcare applications.

By Qianchu Liu, Sheng Zhang, Guanghui Qin, Jeya Maria Jose Valanarasu, Maximilian Rokuss, Mingyu Lu, Timothy Ossowski, Juan Manuel Zambrano Chaves, Cliff Wong, Peniel Argaw, Yashna Hasija, Mu Wei, Wen-wai Yim, Qin Liu, Zilin Jing, Jason Entenmann, Naoto Usuyama, Tristan Naumann, Hoifung Poon
arXiv AI
Jul 20

Cura 1T: Specialized Model for Agentic Healthcare

arXiv:2607. 15314v1 Announce Type: new Abstract: Healthcare spans high-stakes communication, expert reasoning, and workflow execution, yet specialized LLMs that cover these use cases together remain limited.

By actAVA AI, :, Haolin Chen, Leon Qi, Steve Brown, Deon Metelski, Tao Xia, Joonyul Lee, Qixuan Wang, Kevin Riley, Frank Wang, Weiran Yao
Hugging Face Trending Papers
Jun 30

HealthAgentBench: A Unified Benchmark Suite of Realistic Agentic Healthcare Environments for Challenging Frontier AI Agents

As AI agents become increasingly capable of complex, long-horizon reasoning, rigorous and holistic evaluation is essential for measuring progress toward real-world healthcare applications. We introduce HealthAgentBench, a suite of 54 agentic healthcare tasks across 7 categories each with its unique environment.

Hugging Face Trending Papers
Jun 8

Experience Makes Skillful: Enabling Generalizable Medical Agent Reasoning via Self-Evolving Skill Memory

Medical agent systems are increasingly expected to support interactive clinical decision making rather than only static question answering. In such settings, effective agents must reuse prior experience across evolving cases, yet existing memory mechanisms often retain raw historical traces that are redundant, noisy, and difficult to govern.

arXiv Computation and Language
5d ago

MedResearcher-R1: Expert-Level Medical Deep Researcher via A Knowledge-Informed Trajectory Synthesis Framework

MedResearcher‑R1 is a medical deep‑research agent that uses a Knowledge‑Informed Trajectory Synthesis (KISA) framework to build medical knowledge graphs and generate complex multi‑hop question‑answer pairs, especially for rare medical entities. It also incorporates a medical retrieval engine and general‑purpose tools to reliably synthesize medical evidence. The resulting 2,100+ trajectories across 12 specialties enable supervised fine‑tuning and reinforcement learning, producing a 32B model that outperforms larger proprietary systems on MedBrowseComp and shows strong performance on GAIA and xBench benchmarks.

By Ailing Yu, HaoYang Hong, Lan Yao, Jingnan Liu, Zhe Chen, Jiajun Yin, Yuan Wang, Xinhao Liao, Zhiling Ye, Ji Li, Yun Yue, Hansong Xiao, Hualei Zhou, Chunxiao Guo, Peng Wei, Junwei Liu, Jinjie Gu
arXiv Computation and Language
Sep 28

PIA: A Personal Intelligence Agent Turning Health Conversations into Records and Records into Understanding

PIA is a personal intelligence agent that works alongside a consumer health agent to convert health conversations into structured clinical records and to transform those records into a synthesized understanding of the user. It uses a memory system with four controls—extraction, memory, retrieval, and understanding—each supported by a health module that includes a schema, medical alias dictionary, knowledge graph, and temporal rules. The agent demonstrates that deeper memory injection—from simple recall to a health snapshot to a causal trajectory—yields progressively richer answers, while also revealing challenges such as missing self‑reported data, the influence of question phrasing, and the presence of structural noise in causal links.

By Jeonghun Yoon, Dongchan Kim, Hongyeon Yu, Young-Bum Kim, Jaegul Choo
arXiv AI
Sep 15

ClinAgent: A ReAct-Based Agent for Conversational Access to Clinical Trial Information

ClinAgent is a conversational system that uses a ReAct-based LLM agent to retrieve and synthesize clinical trial information from multiple sources such as ClinicalTrials.gov, PubMed, and a local dataset. The agent iteratively reasons over user queries, selects appropriate tools, and refines its actions to provide grounded, up-to-date responses in natural language across multi-turn interactions. Evaluation across three phases shows that DeepSeek (thinking mode) excels in planning quality while Gemini 3.0 Flash delivers the highest overall performance and expert ratings, demonstrating the promise of agentic AI for improving clinical trial data access.

By Antonino Vaccarella, Riccardo Cantini, Domenico Talia, Paolo Trunfio, Marianna Talia, Rosamaria Lappano, Marcello Maggiolini
arXiv AI
Jun 17

RubricsTree: Scalable and Evolving Open-Ended Evaluation of Personal Health Agents across Health Memory and Medical Skills

arXiv:2606. 18203v1 Announce Type: cross Abstract: The LLM-empowered personal health agents with user health (sensor) metrics have offered a promising pathway to alleviate global disparities in healthcare access.

By Weizhi Zhang, Zechen Li, Hamid Palangi, Ben Graef, A. Ali Heydari, Simon A. Lee, Salman Rahman, Ray Luo, Zeinab Esmaeilpour, Erik Schenck, Chloe Zhang, Yamin Li, Menglian Zhou, Philip S. Yu, Daniel McDuff, Lindsey Sunden, Mark Malhotra, Shwetak Patel, Ahmed A. Metwally
arXiv AI
Jun 24

BioMedArena: An Open-source Toolkit for Building and Evaluating Biomedical Deep Research Agents

arXiv:2605. 06177v2 Announce Type: replace Abstract: Reproducing and comparing deep research agents today is hard: the same backbone evaluated on the same benchmark can report different accuracies across papers because the harness and tool registry differ, and integrating a new model into a comparable evaluation surface costs weeks of model-specific engineering.

By Jinge Wu, Hongjian Zhou, Mingde Zeng, Jiayuan Zhu, Junde Wu, Jiazhen Pan, Ayush Noori, Sean Wu, Honghan Wu, Fenglin Liu, David A. Clifton