Whole-slide image (WSI) reasoning requires an agent to sequentially acquire visual evidence before answering a diagnostic question. Existing training-free agentic frameworks formulate this process as iterative patch retrieval based on semantic relevance to the question.
arXiv:2608. 14015v1 Announce Type: cross Abstract: Understanding tens-of-minutes surgical videos requires long-horizon temporal reasoning, answering what happens before, after, or across stages of a procedure by grounding the question in visual evidence spread across time.
By Yingying Fan, Penghui Du, Leyan Zhu, Runze He, Zimeng Wu, Yuxuan Zhang, Liang Chen, Jiahao Xie, Jiangtang Wang, Shuai Shao, Anchao Yang, Yutong Bai, Yan Wang
arXiv:2512. 14157v2 Announce Type: replace Abstract: Recent medical MLLMs have made significant progress in generating step-by-step textual reasoning chains.
By Yankai Jiang, Yujie Zhang, Peng Zhang, Wenjie Li, Yichen Li, Jintai Chen, Xiaoming Shi, Shihui Zhen
arXiv:2606. 12169v1 Announce Type: cross Abstract: High-stakes clinical use of large vision-language models (LVLMs) requires reasoning that is grounded in visual evidence and clinical knowledge, not just correct final answers.
By Negin Baghbanzadeh, Pritam Sarkar, Michael Colacci, Abeer Badawi, Adibvafa Fallahpour, Arash Afkanpour, Leonid Sigal, Ali Etemad, Elham Dolatabadi
arXiv:2607. 23794v1 Announce Type: cross Abstract: Pathological diagnosis is inherently multi-scale, requiring the integration of global tissue architecture at low magnification with cellular morphology at higher magnification.
By Chi Phan, Tianyi Zhang, Yufeng Wu, Qiaochu Xue, Jiajie Zhang, Linghan Cai, Zeyu Liu, Sudong Wang, Yueming Jin, Dan Hu
arXiv:2607. 19261v1 Announce Type: cross Abstract: Whole-slide image (WSI) diagnosis requires identifying diagnostically relevant regions, examining them across magnifications, and integrating multi-scale evidence.
By Dankai Liao, Tianyi Zhang, Yufeng Wu, Xinyue Zhang, Qiaochu Xue, Zeyu Liu, Dachun Zhao, Linghan Cai, Yueming Jin
arXiv:2606. 01961v1 Announce Type: new Abstract: Autonomous agents are increasingly expected to support end-to-end medical-AI research workflows, moving beyond isolated prediction tasks or short-form clinical question answering.
By Junqi Liu, Salena Song, Yuhan Wang, Jiawei Mao, Hardy Chen, Xiaoke Huang, Tianhao Qi, Pengfei Guo, Yucheng Tang, Yufan He, Can Zhao, Andriy Myronenko, Dong Yang, Daguang Xu, Yuyin Zhou
arXiv:2604. 09757v2 Announce Type: replace-cross Abstract: Medical vision--language models (VLMs) have shown strong potential for medical visual question answering (VQA), yet their reasoning remains largely text-centric: images are encoded once as static context, and subsequent inference is dominated by language.
By Suyang Xi, Songtao Hu, Yuxiang Lai, Wangyun Dan, Yaqi Liu, Shansong Wang, Xiaofeng Yang
Whole-slide image (WSI) diagnosis requires identifying diagnostically relevant regions, examining them across magnifications, and integrating multi-scale evidence. However, most existing pathology benchmarks evaluate models on pre-cropped patches or pre-extracted slide features, leaving their ability to acquire evidence directly from gigapixel WSIs largely untested.
Pathological diagnosis is inherently multi-scale, requiring the integration of global tissue architecture at low magnification with cellular morphology at higher magnification. However, existing pathology benchmarks and vision-language models (VLMs) are still largely developed under single-scale settings, limiting their ability to learn clinically meaningful multi-magnification reasoning.
arXiv:2606. 11702v1 Announce Type: cross Abstract: To make clinically grounded decisions, medical AI agents are expected to go beyond simple recognition and be capable of tool retrieval, evidence acquisition, and integration.
By Tajamul Ashraf, Hyewon Jeong, Fida Mohammad Thoker, Bernard Ghanem
arXiv:2603. 16250v2 Announce Type: replace-cross Abstract: LVLMs encounter significant challenges in image understanding and visual reasoning, leading to critical perception failures.
By Jaechang Kim, Yotaro Shimose, Zhao Wang, Kuang-Da Wang, Jungseul Ok, Shingo Takamatsu