arXiv:2609.39566v1 Announce Type: new Abstract: Foundation models can serve as clinical agents through tool-use harnesses. However, conventional medical benchmarks assess reasoning over preselected e...
arXiv:2603. 01131v3 Announce Type: replace-cross Abstract: Clinical diagnosis is a gradual process of evidence integration, in which physicians move from symptoms and medical history to examinations, competing hypotheses, disease relations, and treatment decisions.
arXiv:2608.21948v1 Announce Type: new Abstract: Complex clinical reasoning requires models to update diagnostic hypotheses as new evidence emerges and to coordinate different medical specialities und...
The paper introduces MedTraj, a framework that constructs, evaluates, and optimizes multi‑step reasoning trajectories for medical AI agents. It parses each trajectory into observations, evidence, numbered steps, and a conclusion, scoring them on coherence, evidence support, hallucination, completeness, and traceability. Experiments on CareQA, PubMedQA, and CECMed show that incorporating quality‑weighted trajectory context improves reasoning coherence and correctness while significantly reducing hallucinations.
arXiv:2606. 28692v1 Announce Type: new Abstract: Treatment reasoning underpins every therapeutic decision, integrating disease context, comorbidities, medications, contraindications, and evolving biomedical knowledge to select an appropriate therapy.
arXiv:2607. 18999v1 Announce Type: cross Abstract: Multi-turn medical consultation agents must decide what to ask, adapt to patient responses, and determine when the collected evidence is sufficient.
EviDx is a new framework for evidence-aware active diagnosis that pairs patient-specific diagnostic environments with a clinical scaffold and an observer-guided runtime harness. The framework constructs interactive environments from raw clinical cases, organizes role-specialized agents and evidence tools, and regulates diagnostic termination by tracking uncertainty and evidence coverage. Experiments demonstrate that EviDx improves diagnostic performance and process stability while revealing model-dependent capability boundaries.
arXiv:2607. 15280v1 Announce Type: new Abstract: Sequential diagnosis requires balancing diagnostic accuracy against resource costs through iterative information gathering.
The paper introduces MACD, a Multi-Agent Clinical Diagnosis framework that enables large language models to self‑learn clinical knowledge through a multi‑agent pipeline of summarization, refinement, and application. MACD is extended into a human‑AI collaborative workflow where multiple diagnostician agents consult iteratively, guided by a judge agent and human oversight. Evaluation on the MIMIC‑MACD cohort shows significant gains in diagnostic accuracy—an average 11.6 percentage‑point improvement over authoritative knowledge for open‑weight LLMs and an 18.3‑percentage‑point boost over physician‑only diagnosis in text‑only vignettes.
arXiv:2609.15161v1 Announce Type: cross Abstract: Large language model (LLM) driven multi-agent systems have shown promise in complex clinical reasoning, yet existing approaches rely on static strate...
arXiv:2604. 26283v3 Announce Type: replace-cross Abstract: High-precision medical diagnosis relies not only on static imaging features but also on the implicit diagnostic memory experts instantly invoke during image interpretation.
STRIVE is a new framework for longitudinal radiology report generation that separates clinical reasoning into distinct Diagnosis, Attribute, and Temporal Change agents, each producing explicit evidence. The Temporal Change agent is refined with a Progression-Aware GRPO reward that differentiates direction-preserving errors from reversals. Verification occurs twice: a Consistency Gate aligns agent outputs before report generation, and a Validation Agent ensures the final report is supported by the aggregated evidence. On the Longitudinal-MIMIC dataset, STRIVE achieves superior clinical efficacy and more than doubles Longitudinal Change Concordance compared to the strongest baseline.