Deterministic Integrity Gates for LLM-Assisted Clinical Manuscript Preparation: An Auditable Biomedical Informatics Architecture
arXiv:2606. 09500v1 Announce Type: new Abstract: Objective.
The paper introduces a source‑grounded integrity gate for AI‑assisted personal health records, ensuring that data generated by large language models remains provisional until a deterministic monitor verifies it against the source document. The monitor only accepts candidates that contain a unique supporting quotation, appear within the same laboratory row, and preserve provenance, preventing the model from approving its own output. In Medical DataCloud, the system passed all 22 conformance and mutation tests and, in a replay of nine historical lab reports, admitted 72 of 97 numeric candidates while retaining 25 for human review.
arXiv:2606. 09500v1 Announce Type: new Abstract: Objective.
arXiv:2608. 07796v1 Announce Type: new Abstract: Large language models perform strongly on medical knowledge benchmarks, but reliable clinical deployment requires agents to conduct defensible investigations over heterogeneous, longitudinal records: determining what evidence is needed, retrieving and reconciling structured and free-text data, grounding conclusions in verifiable evidence, and deferring cases that cannot be resolved reliably.
arXiv:2606. 14149v1 Announce Type: new Abstract: Large Language Models (LLMs) are increasingly deployed in healthcare settings, yet their tendency to hallucinate poses risks when clinical decisions are involved.
arXiv:2607. 14890v1 Announce Type: new Abstract: Autonomous coding agents increasingly execute multi-step software work, but lifecycle states such as reviewed, tested, DONE, and ready-to-merge remain claims unless supported by current evidence.
arXiv:2607. 09349v1 Announce Type: cross Abstract: Retrieval-augmented generation evaluation checks whether model claims are factually grounded in retrieved documents.
arXiv:2608. 05235v1 Announce Type: cross Abstract: Research agents increasingly conduct multi-round machine-learning experiments in industrial recommendation settings and retain the resulting trajectories to guide later decisions.
The paper introduces MIMIC-DOS, a dataset derived from MIMIC-IV that focuses on ICU cases where patient symptoms and medical signs are discordant. It presents CARE, a privacy‑compliant multi‑stage agentic reasoning framework that uses a proprietary LLM to generate structured categories and transitions, while a local LLM performs evidence acquisition and decision‑making. In retrospective evaluations on MIMIC‑DOS, CARE outperforms other LLMs and agentic workflows, demonstrating stronger handling of conflicting clinical evidence while preserving patient privacy.
arXiv:2607. 09682v1 Announce Type: new Abstract: AI systems are increasingly used to assist consequential decisions in regulated domains such as auditing, finance, and healthcare.
arXiv:2608. 12360v1 Announce Type: cross Abstract: Background: AI/ML-enabled medical devices are increasingly deployed in healthcare under evolving regulatory frameworks.
The paper introduces ClaimReceipt, a specification and verifier that checks whether a claim in an agent evaluation can be recomputed from retained evidence (sufficiency) and whether the evidence covers the entire experiment set (coverage). Using the CR‑2 verifier on 1,392 historical records, the authors demonstrate accurate reproduction of audit verdicts, non‑redundant field groups, and zero false positives on semantic faults. In a prospective CR‑3 run, the system correctly flags missing receipts and preserves coverage when private evidence is withheld, while adding minimal overhead to inference time and transaction size.
arXiv:2606. 18037v1 Announce Type: new Abstract: Tool-using LLM agents increasingly use the Model Context Protocol (MCP) to answer from heterogeneous evidence sources, including search, APIs, databases, clinical records, and formulary tools.
arXiv:2607. 24371v1 Announce Type: cross Abstract: Healthcare interoperability requires AI systems to produce structured outputs conforming to standardized schemas including ICD-10 for diagnostic coding, CPT for procedure billing, and HL7 FHIR for data exchange.