Merlin Plus is a new, large-scale CT dataset that provides radiologist‑created tumor masks for nine different organs, adding 1,153 per‑voxel masks and longitudinal metadata to the existing Merlin collection. The dataset was built using a report‑based active‑learning framework, where radiology reports flag tumor cases, a segmentation model generates initial masks, and radiologists review and correct them, thereby reducing annotation effort while preserving high quality. The added longitudinal data enables temporal modeling of cancer progression, supporting scalable multi‑organ cancer detection, segmentation, and longitudinal analysis in CT.
By Pedro R. A. S. Bassi, Wenxuan Li, Szymon Plotka, Ruby Honjol, Jakub Przado, Xinze Zhou, Kang Wang, Yang Yang, Malte Jensen, Akshay S. Chaudhari, Curtis P. Langlotz, Alan L. Yuille, Zongwei Zhou
arXiv:2505.03380v2 Announce Type: replace
Abstract: Accurate delineation of tumors and surrounding organs-at-risk is essential for radiotherapy, surgery and treatment response assessment, yet remains...
By Haonan Wang, Jiaji Mao, Lehan Wang, Qixiang Zhang, Marawan Elbatel, Yi Qin, Huijun Hu, Baoxun Li, Wenhui Deng, Weifeng Qin, Hongrui Li, Jialin Liang, Jun Shen, Xiaomeng Li
The paper presents an automated segmentation pipeline for whole‑slide histopathology images of colorectal cancer, labeling tumor grades 1‑3 and normal mucosa. It employs dense prediction transformers with multiple encoder backbones, overlapping patches, test‑time augmentation, and an adaptive augmentation policy guided by large language models. The approach, combined with soft‑voting ensembles and post‑processing refinements, raises the F1 score from 62.92 to 69.84 on a colorectal cancer grade dataset.
By \"Umit Mert \c{C}a\u{g}lar, Alptekin Temizel
arXiv:2408.07988v3 Announce Type: replace
Abstract: Despite significant research efforts and advancements, cancer remains a leading cause of mortality. Early cancer prediction has become a crucial fo...
By Samta Rani, Tanvir Ahmad, Sarfaraz Masood, Chandni Saxena
arXiv:2512. 08216v4 Announce Type: replace-cross Abstract: Accurate segmentation of lung tumors from 3D computed tomography (CT) scans is essential for automated treatment planning and response assessment.
By Aneesh Rangnekar, Harini Veeraraghavan
arXiv:2608.30844v1 Announce Type: cross
Abstract: Interactive lesion segmentation in whole-body PET/CT requires a model to provide a strong initial prediction while also responding efficiently to spa...
By Xinglong Liang, Chunyao Lu, Tianyu Zhang, Jiaju Huang, Tao Tan, Yunchao Yin, Lishan Cai
The study evaluates four deep‑learning segmentation architectures—Unet, PSPNet, Linknet, and FPN—paired with six pre‑trained encoders to predict COVID‑19 lesions in CT images. Experiments on three COVID‑19 CT datasets show high accuracy, achieving a maximum binary F1‑score of 98% and multi‑class F1‑scores of 75% and 77%. The work aims to provide a standardized performance benchmark for medical image segmentation and a reference for other imaging scenarios.
By Sarmad Khan, Basim Azam, Arslan Shaukat
Colorectal cancer (CRC) is the second most deadly and third most common cancer, and the leading cause of death among gastrointestinal cancers. Early diagnosis is crucial for the treatment of this canc...
arXiv:2512. 14937v2 Announce Type: replace-cross Abstract: Gliomas are the most common malignant brain tumors in adults and are among the most lethal.
By Abhijeet Parida, Daniel Capell\'an-Mart\'in, Zhifan Jiang, Nishad Kulkarni, Krithika Iyer, Austin Tapp, Syed Muhammad Anwar, Mar\'ia J. Ledesma-Carbayo, Marius George Linguraru
arXiv:2609.25850v1 Announce Type: new
Abstract: Deep learning performance generally improves with increasing training data, yet this scaling is fundamentally constrained by annotation cost in large-s...
By Xiaofei Du, Lei Zhang, Shuyu Yan, Manning Wang, Zhijian Song
arXiv:2608. 13690v1 Announce Type: cross Abstract: Medical image segmentation is still largely treated as a vision-only problem, although clinical interpretation often relies on textual knowledge of anatomy, location, appearance, and surrounding context.
By Rafi Ibn Sultan, Hui Zhu, Chengyin Li, Dongxiao Zhu
HERO (Histology Encoder for Robust Representation in Oncology) is a ViT‑G/14 pathology foundation model trained with DINO and iBOT objectives and refined using high‑resolution Gram anchoring on a 500‑million‑tile corpus from about 575,000 clinical whole‑slide images. It demonstrates superior robustness to center, scanner, and stain variation compared to other state‑of‑the‑art foundation models, while maintaining competitive performance on tile‑level classification, segmentation, and gene‑expression prediction. Across 39 slide‑level clinical tasks, HERO ranks first on average and achieves the best average rank across six benchmark frameworks under an equal‑weighted analysis.
By Zhi Li (Caris Life Sciences, Irving, TX, United States), Eghbal Amidi (Caris Life Sciences, Irving, TX, United States), Yating Cheng (Caris Life Sciences, Irving, TX, United States), Tyson Dawson (Caris Life Sciences, Irving, TX, United States), Gorkem Can Ates (Caris Life Sciences, Irving, TX, United States), Shuzhen Kuang (Caris Life Sciences, Irving, TX, United States), Norsang Lama (Caris Life Sciences, Irving, TX, United States), Md Ashequr Rahman (Caris Life Sciences, Irving, TX, United States), Zhiying Lu (Caris Life Sciences, Irving, TX, United States), Elisabeth K. Kong (Caris Life Sciences, Irving, TX, United States), Milan Radovich (Caris Life Sciences, Irving, TX, United States), David Spetzler (Caris Life Sciences, Irving, TX, United States), Matthew Oberley (Caris Life Sciences, Irving, TX, United States), George W. Sledge (Caris Life Sciences, Irving, TX, United States), Ming Chen (Caris Life Sciences, Irving, TX, United States)