arXiv:2607. 17244v1 Announce Type: new Abstract: Longitudinal T cell receptor repertoires contain signals of clonal expansion, contraction, disappearance, and reappearance after immune perturbation.
arXiv:2602. 01051v5 Announce Type: replace Abstract: Repertoire-level analysis of T cell receptors offers a biologically grounded signal for disease detection and immune monitoring, yet practical deployment is impeded by label sparsity, cohort heterogeneity, and the computational burden of adapting large encoders to new tasks.
arXiv:2602. 06323v2 Announce Type: replace Abstract: Epidemiological forecasting from surveillance data is a hard problem and hybridizing mechanistic compartmental models with neural models is a natural direction.
arXiv:2607. 19020v1 Announce Type: cross Abstract: Background: Clinical decision support systems degrade silently as treatment protocols evolve, yet standard adaptation methods treat models as monolithic blocks, unable to distinguish stable patient physiology from shifting institutional practice.
arXiv:2602. 17330v5 Announce Type: replace-cross Abstract: Comparative analysis of adaptive immune repertoires at population scale is hampered by two practical bottlenecks: the near-quadratic cost of pairwise affinity evaluations and dataset imbalances that obscure clinically important minority clonotypes.
arXiv:2608. 17151v1 Announce Type: cross Abstract: Cell mimicry arises when different cell types appear morphologically similar.
arXiv:2606. 30398v1 Announce Type: new Abstract: Accurately predicting the temporal evolution of clinical biomarkers is crucial for the early diagnosis and management of neurodegenerative diseases such as Alzheimer's disease.
arXiv:2606. 04994v1 Announce Type: new Abstract: Accurate computational prediction of T cell receptor (TCR) antigen specificity would transform the study of T cell biology and enable scalable immune engineering, yet existing models lack sufficient sensitivity and specificity for broad applications.
arXiv:2606. 30902v1 Announce Type: cross Abstract: T cell receptor (TCR)-epitope binding prediction is essential for understanding adaptive immunity and developing immunotherapies.
arXiv:2511. 20577v5 Announce Type: replace Abstract: Real-world time series often exhibit strong non-stationarity, complex nonlinear dynamics, and behavior expressed across multiple temporal scales, from rapid local fluctuations to slow-evolving long-range trends.
Accurate computational prediction of T cell receptor (TCR) antigen specificity would transform the study of T cell biology and enable scalable immune engineering, yet existing models lack sufficient sensitivity and specificity for broad applications. A major limitation is the absence of rigorously defined, unseen benchmark datasets that allow unbiased evaluation of model performance and generalizability.
arXiv:2607. 23258v1 Announce Type: new Abstract: Large-scale calcium imaging has created an opportunity to build foundation-style models for neural population dynamics, but a central question remains unresolved: \textbf{whether a model pretrained on one collection of recordings can generalize to new datasets, experimental paradigms, and even species.
arXiv:2604. 07557v2 Announce Type: replace Abstract: Small longitudinal cohorts, common in maternal health, rare diseases, and early-phase trials, limit computational modeling because enrollment is slow and the data are too sparse to train reliable models.