The study explores how adding anatomical priors and active learning can improve the accuracy of deep learning models for segmenting the Clinical Target Volume (CTV) in gastric cancer radiotherapy. Using 100 retrospective CT scans, an nnU‑Net model trained on 10 expert‑contoured cases was enhanced with voxel‑wise anatomical prior maps and iterative active learning over four rounds. The combined approach raised the mean Dice Similarity Coefficient from 0.84 to 0.87, demonstrating that both techniques individually and together improve segmentation performance and generalizability.
By Phillip Chlap, Mark Lee, Trevor Leong, Matthew Field, Jason Dowling, Hang Min, Julie Chu, Jennifer Tan, Phillip K. Tran, Tomas Kron, Annette Haworth, Martin A. Ebert, Shalini K. Vinod, Lois Holloway
The paper introduces RABR-Net, a two‑stage framework that refines biomedical image segmentation boundaries by combining multiple uncertainty measures into a boundary‑aware representation. A gated residual refiner uses this representation to selectively correct uncertain boundary pixels while preserving confident regions, leading to modest but statistically significant improvements in Dice, Boundary Dice, and HD95 metrics on a held‑out test set. Qualitative results show the refiner focuses on uncertain cytoplasm and nucleus boundaries, though calibration does not automatically improve.
By Anima Kujur
arXiv:2606. 03069v1 Announce Type: cross Abstract: Generalized segmentation of medical images prevents performance degradation when different imaging devices and clinical protocols are used across multiple domains.
By Aqsa Naseer, Maryam Bibi, Syeda Samiya Urooj, Muhammad Khurram Shahzad
The paper introduces an unsupervised approach to medical image segmentation by training a Denoising Diffusion Probabilistic Model (DDPM) on 21 unlabeled abdominal CT scans to learn anatomical features. The encoder weights from the DDPM are transferred to a U‑Net for downstream segmentation on the BTCV multi‑organ dataset, resulting in a significant Dice score improvement for liver segmentation from 0.75 to 0.93. In low‑data regimes, diffusion‑pretrained models retain robust performance, achieving high Dice scores even with only 10% of labeled data.
By Akshat G, Divyansh Gupta, Shaleen Bhatnagar, Shilpa Ankalaki, Tusar Kanti Mishra
The paper introduces AdaConRed, a label‑free post‑conformal decision rule that transforms ambiguous conformal prediction sets into single class assignments for medical image classification. It employs a five‑stage pipeline—vision‑language generative augmentation, a frozen DermFoundation encoder, a lightweight MLP classifier, an entropy‑modulated margin‑aware nonconformity score, and a reassignment step for transitional samples—to improve accuracy on OSCC and ISIC benchmarks. Results show notable gains in malignant class accuracy while maintaining overall performance.
By Saibal Ghosh, Samarup Bhattacharya, Sanjoy Kumar Saha, Umapada Pal, Tapabrata Chakraborti
The paper introduces SV-Cine, a cardiac MRI segmentation framework tailored for single ventricle physiology (SVP). It combines a generative data augmentation pipeline that creates synthetic 3D cardiac meshes and MRI, with a diagnosis-conditioned adaptation of the CineMA foundation model that uses patient-level diagnostic information to improve segmentation. Evaluations on an internal cohort show high Dice scores for left and right ventricles, outperforming nnU-Net, and demonstrate that incorporating diagnosis priors can adapt a pretrained model to specialized SVP tasks.
By Lila Cunge, Yuehong Liu, Hang Xu, Thomas Coudert, Pierangelo Renella, J Paul Finn, William Hsu, Kim-Lien Nguyen
Acquiring pixel-level annotations for medical image segmentation is a severe bottleneck. Traditional U-Net architectures, while effective, learn local texture patterns and lack awareness of global ana...
arXiv:2603.13044v2 Announce Type: replace-cross
Abstract: Medical image segmentation (MIS) is a fundamental component of computer-assisted diagnosis and clinical decision support. Over the past decad...
By Vanessa Borst, Anna Riedmann, Samuel Kounev
arXiv:2608. 12274v1 Announce Type: cross Abstract: Background: Accurate segmentation of the Left Anterior Descending (LAD) artery in 3D free-breathing, non-contrast CT is critical for cardiac dose sparing in thoracic radiotherapy.
By Rafi Ibn Sultan, Chengyin Li, Yiannos Demetriou, Ahmed I. Ghanem, Joshua P. Kim, Justine Cunningham, Hassan Bagher-Ebadian, Dongxiao Zhu, Kundan S. Thind
arXiv:2608.29348v1 Announce Type: new
Abstract: Background: Patient details and acquisition metadata are important for clinical decisions, image quality control, and automated research pipelines, but...
By Jakob Wasserthal, Joshy Cyriac, Michael Bach, Kimia Mozahheb Yousefi, Minh-Son To, M\'at\'e Sik, C\'edric H\'emon, Thomas Weikert, Martin Segeroth
The study investigates how few expert-annotated cases are needed to fine‑tune MedSAM3 for abdominal organ segmentation using Low‑Rank Adaptation (LoRA). With only 10 annotated CT or MRI cases, the LoRA‑adapted models achieve performance comparable to specialist systems that require orders of magnitude more data, including reliable gallbladder segmentation and near‑state‑of‑the‑art results for liver, kidneys, and spleen. The approach also generalizes to cardiac segmentation on the Whole Heart dataset, and training takes only 3–5 hours per organ on a single GPU, roughly twice as fast as nnU-Net.
By Sachin Dudda Nagaraju, Bendik Skarre Abrahamsen, Ashkan Moradi, Mattijs Elschot
arXiv:2602.20773v2 Announce Type: replace
Abstract: Purpose: Developing generalizable medical image segmentation models is challenging because imaging data are distributed across institutions and dif...
By Sachin Dudda Nagaraju, Ashkan Moradi, Bendik Skarre Abrahamsen, Mattijs Elschot