arXiv Machine Learning

Learning Hybrid Biophysical Neuron Models with Neural ODEs

arXiv:2606. 16693v1 Announce Type: cross Abstract: Biophysical neuron models link measurements of neural activity to underlying cellular mechanisms.

arXiv Machine Learning
Aug 5

A Physics-Flavored Transformer Network for Parametrizing Contraction Dynamics of Engineered Skeletal Muscle Tissues

arXiv:2608. 03927v1 Announce Type: new Abstract: Engineered Skeletal Muscle Tissues (ESMs) have become a key structure for biomedical disease modeling and pharmacological screening, yet their functional characterization often relies on simplistic metrics like peak force, discarding critical kinetic information.

By Mattias Luber, Timo Betz
arXiv Machine Learning
Sep 22

A discrete generative model of neuronal spiking activity on microelectrode arrays

The paper presents a discrete generative model for neuronal spiking activity recorded on microelectrode arrays. It uses a shared vocabulary of spatiotemporal motifs learned by a residual vector‑quantized autoencoder and predicts motif occurrence with a factorized masked transformer. Evaluated on 31 assays from human brain organoids and ex vivo hippocampal tissue, the model achieves superior reconstruction and generation performance compared to baselines and shows that motifs are largely reused across assays.

By Md Sayed Tanveer, Mohammed A. Mostajo-Radji, Ge Wang
arXiv AI
2d ago

SpikeMoE: Brain-Inspired Competitive Routing for Flexible Spiking Mixture-of-Experts

SpikeMoE introduces a spike-based k‑WTA router that uses lateral inhibition and refractory periods to select the top‑K experts based on discrete spike counts, inspired by hippocampal CA1 competition. The framework combines spiking neural network dynamics with mixture‑of‑experts conditional computation and adds a two‑stage missing‑modality module for robust multimodal processing. Experiments on vision, language, and multimodal tasks show that SpikeMoE matches or surpasses ANN baselines while offering energy‑efficient performance.

By Xiaoli Liu, Yujie Liang, Jialin Li, Malu Zhang
arXiv Machine Learning
Jul 17

RTS Smoother-Guided Learning of Physics-Based Neural Differential Models

arXiv:2607. 15180v1 Announce Type: new Abstract: Ordinary differential equations (ODEs) are widely used to model dynamical systems in physics, biology, neuroscience, and physiology, but in many applications some equations of the dynamics are unknown and only a subset of the state variables are measured.

By Ahmet Demirkaya, Georgios Stratis, Tales Imbiriba, Zachary D. Danziger, Deniz Erdogmus
arXiv AI
Sep 21

Continuous Spiking Graph Neural Networks

arXiv:2404.01897v3 Announce Type: replace-cross Abstract: Continuous graph neural networks (CGNNs) have garnered significant attention due to their ability to generalize existing discrete graph neura...

By Shiqi Fan, Zeqing Zhang, Nan Yin, Tong Li, Hongyi Nie, Die Hu, Wen Hua
arXiv AI
Jul 15

BattVAE-GP: Generative Modeling of Long-Horizon Battery Degradation with Uncertainty Quantification

arXiv:2607. 11943v1 Announce Type: cross Abstract: Long-horizon physics-based simulations of battery degradation provide mechanistic insight but remain computationally expensive, limiting their use for dense exploration of operating conditions over extended cycle life.

By Raghvender Raghvender, Mahdi Abid, Ferran Brosa Planella, Charles Delacourt, Arnaud Demorti\`ere
arXiv AI
Jun 2

Rare Events, Real Signals: Functional Ensembles as Units of Computation in Deep Spiking Networks

arXiv:2606. 00073v1 Announce Type: cross Abstract: We investigate how internal representations emerge across hierarchical processing systems by introducing a neuroscience-inspired framework for analyzing deep spiking neural networks (SNN) through the lens of functional connectivity.

By Aditi Aravind, Konstantinos Ladakis, Mario Alexios Savaglio, Stelios M. Smirnakis, Maria Papadopouli