arXiv Machine Learning

CHARTER: Auditing Reference Substitution in Hierarchical Compact-Evidence Evaluation for Computational Pathology

arXiv Machine Learning
Jul 30

Rethinking Clinical Relevance in Chest X-ray Machine Learning: How Evaluation References Define Performance

arXiv:2607. 26333v1 Announce Type: cross Abstract: Chest X-ray (CXR) machine learning relies heavily on automated evaluation using reference standards that aim to approximate clinical judgment.

By Panagiotis Fytas, Ian Selby, Clemens Karner, Judith Babar, Simon Baker, Jake Beckford, Timothy J. Sadler, Shahab Shahipasand, Arthikkaa Thavakumar, John Li Chen, Alex Sawer, Michael Roberts, Jonathan Weir-McCall, J. H. F. Rudd, Carola-Bibiane Sch\"onlieb, Anna Korhonen, Anna Breger
arXiv AI
Sep 17

Reporting Practice Matters: The Impact of Reference Choice on Chest X-ray Report Evaluation

The study examines how differences in radiologists’ reporting styles—such as terminology, shorthand, formatting, and detail—affect the evaluation of AI-generated chest X‑ray reports. By quantifying the sensitivity of common metrics to these variations, the authors show that changes in reference reports can shift model rankings. They introduce a taxonomy of reporting variations and a rewriting method, ReRef, that preserves clinical meaning while altering style, and release a validated dataset of paired reference reports to aid future research.

By Daniel P. Jeong, Charles Q. Li, Hossein Hosseiny, Nitya M. Bhalla, Fatma Uyar Morency, Pradeep Ravikumar, Zachary C. Lipton, Michael Oberst
arXiv AI
Jul 17

Demographically-Conditioned Synthetic Medical Images for Bias Mitigation and Bias Detection in Disease Classifiers

arXiv:2607. 14984v1 Announce Type: new Abstract: Per-subgroup fairness audits of medical image classifiers face a sample-size problem: minority subgroups in held-out test sets have so few samples that the resulting confidence intervals on per-subgroup performance are wider than the bias the audit is meant to detect.

By Mahmoud Ibrahim, Bart Elen, Chang Sun, Gokhan Ertaylan, Michel Dumontier
arXiv Machine Learning
Sep 24

Discover, Falsify, Revise: Auditing Input-Use Claims from Source Code to Predictive Contribution in Agent-Discovered Cell Models

The paper introduces CELLAUDIT, a method for auditing whether inputs claimed to influence predictive models actually do so. By testing if an input can enter the computation, whether predictions depend on it, and if that dependence improves observed responses, the authors evaluate agent-generated predictors on a morphology‑transcriptomics benchmark (BBBC047). Their findings show that many models claim compound contributions that are not supported by the data, and that falsification‑guided revisions can recover genuine input effects while improving performance.

By Mengran Li, Bo Li, Chengyang Zhang, Yang Yan, Jinfeng Xu, Zhenchao Tang
arXiv Machine Learning
3d ago

Beyond the Dominant Label: Recovering Coexisting Lesion Evidence with Multiple Instance Learning

The paper introduces DomSet-MIL, a multiple instance learning framework designed to recover evidence of coexisting lesions in whole-slide images when only the most severe diagnosis is weakly supervised. It models the dominant-label mechanism through a censored likelihood that treats the reported diagnosis as the maximum severity without assuming other lesions are absent, and employs severity-ordered residual routing with top‑q pooling to preserve secondary findings. Experiments on natural and controlled datasets show that DomSet-MIL outperforms standard MIL approaches in dominant-label prediction while better recovering latent coexisting-lesion evidence.

By Lubin Gan, Jing Zhang, Xinming Zhang, Chengpeng Xu, Siying Wu, Xiaoyan Sun
arXiv AI
Aug 11

From Trajectories to Evidence: Auditable Experimental Records for Industrial Research Agents

arXiv:2608. 05235v1 Announce Type: cross Abstract: Research agents increasingly conduct multi-round machine-learning experiments in industrial recommendation settings and retain the resulting trajectories to guide later decisions.

By Zijie Zhuang, Changxin Lao, Pengbo Xu, Hanwen Xu, Ruochen Yang, Yingzhi He, Peng Zhang, Jiangxia Cao, Yusheng Huang, Guohong Mu, Jian Liang, Ruiming Tang, Shuang Yang, Zhaojie Liu, Wenwu Ou, Kun Gai
arXiv AI
Jul 24

Auditing Evidence Use in Medical LLM Diagnosis

arXiv:2607. 20848v1 Announce Type: new Abstract: Medical LLMs are often evaluated by whether they select the correct diagnosis, but diagnostic accuracy alone does not show whether the model used the case evidence appropriately.

By Junchi Liao, Jiawen Deng, Fuji Ren
arXiv Computer Vision
Aug 27

Label-Free Foundational Model Selection for Medical Image Classification under Distribution Shift via Pseudo Label Discrepancy

The paper introduces a label‑free method called AURCC for selecting the best foundational model for medical image classification when the target domain lacks labels. AURCC uses a pseudo‑label discrepancy computed by the SUDO framework to score models without fine‑tuning. Experiments on chest X‑ray data across three inter‑hospital shifts show that AURCC closely matches the true model ranking, outperforming simple source‑accuracy baselines especially when source data are limited.

By Juan I\~naki Larrea, Lucas Mansilla, Enzo Ferrante