arXiv:2606.13945v2 Announce Type: replace
Abstract: Rare diseases affect over $300$ million patients across more than $7{,}000$ conditions, yet no single hospital encounters enough cases of any one c...
By Ziqing Wang, Lili Zhao, Kaize Ding
The paper introduces MIMIC-DOS, a dataset derived from MIMIC-IV that focuses on ICU cases where patient symptoms and medical signs are discordant. It presents CARE, a privacy‑compliant multi‑stage agentic reasoning framework that uses a proprietary LLM to generate structured categories and transitions, while a local LLM performs evidence acquisition and decision‑making. In retrospective evaluations on MIMIC‑DOS, CARE outperforms other LLMs and agentic workflows, demonstrating stronger handling of conflicting clinical evidence while preserving patient privacy.
By Haochen Liu, Weien Li, Rui Song, Zeyu Li, Chun Jason Xue, Xiao-Yang Liu, Sam Nallaperuma-Herzberg, Xue Liu, Ye Yuan
arXiv:2607. 15314v1 Announce Type: new Abstract: Healthcare spans high-stakes communication, expert reasoning, and workflow execution, yet specialized LLMs that cover these use cases together remain limited.
By actAVA AI, :, Haolin Chen, Leon Qi, Steve Brown, Deon Metelski, Tao Xia, Joonyul Lee, Qixuan Wang, Kevin Riley, Frank Wang, Weiran Yao
EviDx is a new framework for evidence-aware active diagnosis that pairs patient-specific diagnostic environments with a clinical scaffold and an observer-guided runtime harness. The framework constructs interactive environments from raw clinical cases, organizes role-specialized agents and evidence tools, and regulates diagnostic termination by tracking uncertainty and evidence coverage. Experiments demonstrate that EviDx improves diagnostic performance and process stability while revealing model-dependent capability boundaries.
By Lihang Zeng, Shaoting Zhang, Xiaofan Zhang
arXiv:2607. 24419v1 Announce Type: new Abstract: Deep models have substantially advanced 12-lead ECG classification, yet their refinement still relies heavily on human experts to inspect failures and iteratively revise classifier designs.
By Jinliang Deng, Yiming Niu, Yibo Pan, Zhiqi Shao, Qin Luo, Yongxin Tong
arXiv:2606. 18613v1 Announce Type: cross Abstract: The most plausible near-term role of medical LLMs is to assist rather than replace physicians, yet current evaluations often test isolated capabilities: clinical knowledge, EHR system interaction, or patient communication.
By Tianming Du, Peijie Yu, Sihan Shang, Danli Shi, My Linh Nguyen, Shengbo Gao, Guangyuan Li, Yinghong Yu, Yan Jiang, Qianlong Zhao, Behzad Bozorgtabar, Shaoxiong Ji, Jiazhen Pan, Daniel Rueckert, Jiancheng Yang
arXiv:2609.00296v1 Announce Type: new
Abstract: Large language model (LLM) agents are increasingly proposed for healthcare tasks such as clinical documentation, evidence retrieval, patient messaging,...
By Junyi Yao, Baichuan Li, Zihao Zheng, Jiayu Long
arXiv:2608. 05893v1 Announce Type: new Abstract: Electrocardiography (ECG) is one of the most widely used non-invasive tools for diagnosing cardiovascular disease, but transforming multi-lead ECG recordings into reliable clinical reports remains challenging.
By Akanta Das, Tasinul Islam Ahon, Ahmed Mahir Sultan Rumi, Md Mahbubur Rahman, Tausif Amim Shadly, Tanzima Hashem
arXiv:2609.22164v1 Announce Type: cross
Abstract: Structured EHR is abundant but sparse, coded, and difficult to use directly for note-centric clinical modeling. We present MedNotes, a multi-agent sy...
By Nina Fatehi, Reihaneh Hassanzadeh, Meysam Ghaffari, Animesh Agarwal, Carlos Morato
EHR2Trace is a system that transforms electronic health records from multiple sources into a standardized, traceable event format suitable for training and evaluating patient world models and clinical agents. It links each event to its original record, separates the event time from the time the information became available, and distinguishes between medication orders, dispensing, and administration. The tool supports both OMOP and MEDS data models, includes automated validation, and was tested on three clinical datasets, converting 846.4 million events and detecting all injected faults.
By Xinye Yang, Yuli Wang, Cheng Ting Lin, Harrison Bai
arXiv:2608.27856v1 Announce Type: new
Abstract: Recent advances in large language models are enabling autonomous clinical agents to perform increasingly complex electronic health record (EHR) modelin...
By Jun Bai, Ruilin Wang, Yue Li
arXiv:2609.24620v1 Announce Type: new
Abstract: Answering epidemiological questions from real-world clinical data requires medical coding, schema-aware SQL, and validation of implicit choices about p...
By Angelo Ziletti, Leonardo D'Ambrosi, Melanie Tuchardt, Tim Kondziella