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arXiv Machine Learning

Evaluating Time-Series Foundation Models and Multimodal Dietary Context for CGM Forecasting

The study evaluates time‑series foundation models for continuous glucose monitoring (CGM) forecasting across eight public datasets covering Type 1, Type 2, and non‑diabetes populations. Zero‑shot foundation models did not consistently beat strong task‑specific baselines, but lightweight fine‑tuning of models like Chronos‑Bolt improved root‑mean‑square error by up to 18% in both in‑distribution and out‑of‑distribution settings. Incorporating multimodal dietary context via CGMacros and a residual‑based fusion framework further reduced overall RMSE by ~3% and postprandial RMSE by ~15%, indicating that dietary signals add clinically meaningful value beyond CGM alone.

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arXiv Machine Learning
Aug 27

GlucoFM: A Dual-Stream Foundation Model for Continuous Glucose Monitoring

GlucoFM is a lightweight foundation model for continuous glucose monitoring that aligns irregular CGM data to a 24‑hour grid and splits glucose dynamics into slow‑varying trend and short‑term deviation streams. Pre‑trained on over 109,000 hours of unlabeled recordings, it outperforms existing CGM‑specific models on seven phenotype‑classification tasks, improving average PR‑AUC by 4.1 points and enabling strong cross‑dataset transfer and few‑shot adaptation. When combined with meal, nutrition, and subject context, its frozen encoder delivers the lowest two‑hour postprandial glycemic response errors for trajectory, incremental AUC, peak rise, and peak timing metrics.

By Zechen Li, Keerthana Natarajan, Weizhi Zhang, Menglian Zhou, Simon A. Lee, Yuwei Zhang, Maxwell A. Xu, Zeinab Esmaeilpour, Flora D. Salim, Mark Malhotra, Lindsey Sunden, Shwetak Patel, Yuzhe Yang, Ahmed A. Metwally
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Hugging Face Trending Papers
Sep 8

It's All in the Way You Say It: The Role of Information Representation in LLM-Based Glycemic-Event Prediction

The paper examines how the representation of physiological data affects the performance of large language models (LLMs) in predicting post‑meal blood glucose events for people with type 1 diabetes. Using the OhioT1DM dataset, the authors compare zero‑shot and few‑shot prompt‑based LLMs across 30, 60, and 90‑minute horizons, varying the textual encoding of glucose readings, derived descriptors, and contextual variables such as insulin, meals, carbs, and activity. Results show that while conventional supervised models excel at hyperglycemia prediction, certain prompt‑based LLM configurations outperform them for hypoglycemia, and that the way data is presented to the model is a key determinant of success, with added context not consistently improving outcomes.

llms
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arXiv Machine Learning
Jun 8

GlucoFM-Bench: Benchmarking Time-Series Foundation Models for Blood Glucose Forecasting

arXiv:2606. 06881v1 Announce Type: new Abstract: Blood glucose forecasting models are foundational for modern diabetes management systems, as reliable short-term predictions can enable proactive interventions, support automated insulin delivery, and reduce the risk of hypo- and hyperglycemic events.

By Baiying Lu, Zhaohui Liang, Ryan Pontius, Shengpu Tang, Temiloluwa Prioleau
llmsbenchmarks
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arXiv AI
Jun 10

MetaPlate: Counterfactual-Guided RAG-LLM Tool for Personalized Food Recommendation and Hyperglycemia Prevention

arXiv:2606. 10120v1 Announce Type: cross Abstract: Postprandial hyperglycemia is a key risk factor for metabolic disorders; however, existing dietary guidance is often static, impractical, and insufficiently personalized, providing recommendations that are difficult to follow or not impactful.

By Asiful Arefeen, Carol Johnston, Hassan Ghasemzadeh
llmsragmultimodalsafety
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arXiv AI
Sep 23

Predicting Postprandial Glycemic Response from Meal Images, Clinical Variables, and Gut Microbiome Information

The study introduces a multimodal framework that predicts postprandial glycemic response (PPGR) by combining image-derived macronutrient estimates with clinical variables and gut microbiome data. It jointly performs macronutrient estimation from meal images and glucose prediction, using an attention-based module to model interactions between dietary and host-specific information. Evaluated on a real-world dataset, the model outperforms existing PPGR baselines that use image-derived inputs and nearly matches methods relying on manually reported macronutrients.

By Varvara Kondratyeva, Kamilia Zaripova, Nassir Navab, Azade Farshad
multimodal
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