arXiv Machine Learning

CFBrainAug: Modularity-Induced Counterfactual Brain Network Augmentation for Interpretable fMRI-based Autism Diagnosis

arXiv Machine Learning
Sep 29

Supervised Deep Multimodal Matrix Factorization for Interpretable Brain Network Analysis

The paper introduces Supervised Deep Multimodal Matrix Factorization (SD3MF), an interpretable framework that extends Symmetric Nonnegative Matrix Tri-Factorization to supervised prediction across populations of multimodal brain graphs. SD3MF learns deep hierarchical factorizations for each modality and a shared latent representation, jointly optimizing graph reconstruction and prediction while enabling data-driven multimodal fusion. Experiments on multimodal connectome datasets demonstrate that SD3MF outperforms strong deep learning baselines such as CNNs and GNNs, providing biologically interpretable insights through community-level interaction matrices.

By Amjad Seyedi, Lifang He, Songlin Zhao, Akwum Onwunta, Nicolas Gillis
arXiv AI
Sep 28

UniAR: A Unified Framework for Autism Recognition Enhanced by Multi-View Prompt Learning

UniAR is a unified framework that improves autism spectrum disorder (ASD) recognition by using multi-granularity prompt learning and a large multimodal model to generate diagnostic descriptions at word, phrase, and sentence levels. It aligns these semantic representations with visual evidence through a Mixture-of-Experts-based Multi-Scale Alignment Module, enabling robust ASD detection across heterogeneous data types. Experiments on four brain MRI and facial expression benchmarks show that UniAR outperforms state‑of‑the‑art methods, achieving 75.9% accuracy on MRI and 91.6% on facial benchmarks, with gains of 1.5 and 1.2 percentage points respectively.

By Lei Xin, Zeheng Wang, Jiayin Zhu, Shihong Huang, Fanhu Zeng, Changjiang Jiang, Dengbo He, Yutao Yue, Zhenglun Kong
arXiv Machine Learning
Jul 9

Counterfactual Modeling with Fine-Tuned LLMs for Health Intervention Design and Sensor Data Augmentation

arXiv:2601. 14590v3 Announce Type: replace Abstract: Counterfactual explanations (CFEs) provide human-centric interpretability by identifying the minimal, actionable changes required to alter a machine learning model's prediction.

By Shovito Barua Soumma, Asiful Arefeen, Stephanie M. Carpenter, Melanie Hingle, Hassan Ghasemzadeh
arXiv AI
Oct 12

Amortized Counterfactual Prediction with Graph Neural Networks

The paper introduces the Counterfactual Graph Neural Process (CFGNP), an end‑to‑end method that directly answers counterfactual queries from observational data without first estimating a causal graph. CFGNP employs Graph Neural Networks to leverage a dual‑graph structure, limiting cross‑world message passing to matched factual–counterfactual variables. Experiments on synthetic and image‑based datasets, including the German Loan benchmark, show that CFGNP outperforms existing methods, reducing mean‑squared error from $4.51 imes10^{-2}$ to $0.19 imes10^{-2}$, and generalizes from 10‑node to 30‑node graphs without retraining.

By Hendrik Stumpf, Francesco Quinzan
arXiv Machine Learning
Sep 18

HyperAMS-Net: Adaptive Multi-Scale Spatial Hypergraph Network for Brain Disorder Classification

HyperAMS‑Net is a deep learning framework that classifies brain disorders from resting‑state fMRI or structural MRI data. It combines adaptive multi‑scale convolution, hypergraph attention, spatial‑channel attention, and adaptive feature fusion to capture complementary patterns across multiple scales and higher‑order dependencies. Evaluated on ABIDE, REST‑meta‑MDD, and ADNI datasets, it achieves state‑of‑the‑art accuracy and AUC, with ablation studies showing hypergraph attention as the most critical component.

By Proloy Kumar Mondal, Md Kamran Hussin Chowdhury, Hoi Leong Lee
arXiv Machine Learning
Oct 28

Neural-DISCO: Source-Conditioned Counterfactual Editing of Neural Population Activity

Neural‑DISCO is a disentangled representation learning framework that enables source‑conditioned counterfactual editing of neural population activity. By partitioning latent space into label‑specific components and a residual latent, it allows selective editing of behavioral or stimulus labels while preserving other observed labels and intrinsic variability. The method is validated on simulated and real neural recordings, and combined with feature attribution to identify neurons most relevant to each label, improving recovery of known functional cell roles.

By Nico Policzer, James Ho, Joseph Soo, Xin Tang
arXiv AI
Jun 2

Brain-Atlas-Guided Generative Counterfactual Attention for Explainable Cognitive Decline Diagnosis Using Multimodal Connectomes

arXiv:2606. 01237v1 Announce Type: new Abstract: Mild cognitive impairment (MCI) and subjective cognitive decline (SCD) are closely associated with the early Alzheimer's disease continuum, where accurate and explainable diagnosis is important for early risk assessment and intervention.

By Xiongri Shen, Jiaqi Wang, Zhenxi Song, Yi Zhong, Leilei Zhao, Xin He, Baiying Lei, Zhiguo Zhang