arXiv Computation and Language By Verena Jasmin Hallitschke, Carsten Eickhoff, Philipp Berens

Scientific Domain Knowledge Improves Vision-Language Fundus Models

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The paper introduces PubMed-Ophtha, a hierarchical dataset of 102,023 panels with subcaptions from 15,842 open‑access PubMed Central articles, designed to provide high domain density for vision‑language models in ophthalmology. The authors fine‑tuned identical CLIP models on this dataset, on medical reports, and on general biomedical literature, and found that the domain‑specific literature model achieved the best average performance across 110 clinical tasks, with a mean linear probing AUROC of 88.63% versus 85.68% for medical reports. Even when restricting the dataset to fundus images or matching the image count of the medical report dataset, performance remained high, suggesting that the gains stem from the domain density of the literature.

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