AlphaFold has revealed the structure of a key protein behind heart disease
Summary generated by The Flow from the publisher's feed. The full article lives at DeepMind Blog.
Explore how AlphaFold has accelerated science and fueled a global wave of biological discovery.
arXiv:2608. 16094v1 Announce Type: new Abstract: Accurate protein structure prediction is fundamental to structural biology because protein structure underlies molecular function and provides a basis for mechanistic interpretation.
arXiv:2602. 06020v3 Announce Type: replace Abstract: How do protein structure prediction models fold proteins?
arXiv:2607. 16087v1 Announce Type: new Abstract: AlphaFold2's 93 million parameters, shaped by the evolutionary record of protein structure encoded in the Protein Data Bank and in sequence alignments, are conventionally treated only as machinery for converting sequence to structure.
For decades, the existence of the hydrophobic core, a region in the 3D structure of proteins where hydrophobic amino acids reside together, has been considered a general property in proteins. What we have found now may extend that model.
arXiv:2606. 28179v1 Announce Type: cross Abstract: Identifying robust associations between cardiac imaging phenotypes and clinical diseases is fundamental to population-scale cardiovascular research and reliable risk stratification.
