arXiv:2608. 02663v1 Announce Type: cross Abstract: Accurate ICU mortality prediction requires modeling irregular clinical observations across heterogeneous entity types.
By Mohammad Nasir Uddin, Rahnuma Tabassum Orpita, Asaduzzaman Anik, Eklachur Rahman Bhuiyan, Marjahan Risalat, SM Wali Ullah, Asif Ahamed
The paper introduces a bounded updating framework for ICU prediction models that freezes the physiological encoder while allowing updates only to the treatment pathway and fusion head. Experiments on 84,792 MIMIC-IV ICU stays across four temporal shifts show that selective adaptation yields more stable explanations—higher rank correlation, better top‑5 feature agreement, and improved retrieval stability—compared to full model adaptation. Predictive performance varies by outcome, but the results demonstrate that explanation stability is governed by the structural boundaries of allowed adaptation rather than merely by freezing components.
By Fatema Ferdous Tamanna, K. M. Merajul Arefin, Md. Abdul Masud
PGP-Clinical-TimeKAN is a trajectory-first framework for joint probabilistic forecasting of multivariate physiological data, combining missingness-aware temporal encoders, a soft organ-system prior, patient-specific relations, nonlinear Kolmogorov‑Arnold messages, and a low‑rank multivariate Student‑t head. Evaluated on a MIMIC‑IV cohort of 6,882 patients, it achieves the second‑lowest normalized MAE and the lowest RMSE among 13 models, while providing calibrated probabilistic forecasts with empirical coverage at 50%, 80%, and 95% intervals. Ablation studies show that relational structure is critical for performance, and increasing covariance rank improves likelihood but not point accuracy.
whyItMatters":"The model demonstrates that joint trajectory forecasting can yield highly accurate, calibrated predictions of physiological trajectories, offering a potentially inspectable intermediate task for clinical deterioration prediction."
By Weizhi Nie, Rihao Chang, Weijie Wang, Yuting Su
The study introduces a graph‑enhanced framework for discovering disease trajectories and forecasting temporal endpoints using longitudinal EHR data from MIMIC‑IV v3.1. It constructs patient‑specific motifs from consecutive admissions, applies a time‑aware Transformer to select up to 24 motifs per endpoint, and reports modest improvements in micro‑AUPRC and event‑time MAE, with larger gains for events occurring after 730 days. The authors also explore branching‑motif conditioning and GNN‑based edge repair, finding that motifs mainly provide long‑range timing support rather than superior endpoint discrimination or survival prediction.
By Jin-Jia Zheng, Vincent S. Tseng
arXiv:2607. 02938v1 Announce Type: new Abstract: Clinical time series prediction in intensive care units remains challenging due to heterogeneous physiological variables and informative missingness.
By Soyeon Park, Charmgil Hong
arXiv:2608.29301v1 Announce Type: new
Abstract: Predicting future organ dysfunction in Intensive Care Unit (ICU) patients is critical for early clinical intervention, yet existing machine learning ap...
By Razan Albouq, Asra Aslam