arXiv Machine Learning By Junkyung ju, Kyungho Yoon, Minwoo Shin

Physics-Guided Synthetic High-Frequency Ultrasound Generation for Skin Layer Segmentation

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The paper introduces a physics-guided synthetic high‑frequency ultrasound (HFUS) generation framework for skin layer segmentation. It builds multilayer acoustic skin phantoms, assigns layer‑dependent acoustic properties, and uses k‑Wave simulation to produce paired synthetic HFUS images, dense layer masks, and metadata. When used to pretrain segmentation models and fine‑tuned on real HFUS data, the synthetic pretraining yields performance comparable to real‑only training and improves mean Dice/IoU in most architectures, indicating that the synthetic images carry transferable anatomical and textural cues.

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