arXiv AI By Anita Yang, Siu Lun Chau, Tomoya Wakayama, Krikamol Muandet, Masaki Adachi

Open-ended Scientific Discovery with Possibilistic Reasoning

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The paper introduces Abductive Autonomous Scientific Discovery (AASD), a framework that uses possibility theory to guide large language models in generating and testing hypotheses while preserving statistical validity. It defines abductive utility as a computable metric for discovery progress and presents possibility frontier search, the first algorithm for AASD, which maintains anytime validity and asymptotically achieves ε‑optimal abductive utility under suitable conditions. Experiments on both synthetic and real‑world scientific‑discovery tasks demonstrate strong performance of the proposed method.

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