arXiv:2606. 30335v1 Announce Type: new Abstract: Autonomous scientific discovery systems increasingly use large language models (LLMs) to propose new hypotheses, but many such systems condition primarily on experimental memory: archives of high-scoring candidates or heuristic summaries of recent trials.
By Xuening Wu, Shan Yu, Qianya Xu, Shenqin Yin
The paper proposes a distributional theory explaining how large language models (LLMs) incorporate external evidence into their decision-making process. It identifies three key predictions: (1) evidence is more persuasive when it aligns with the model’s prior beliefs, (2) models more readily accept errors from their own internal processes than from external sources, and (3) the same evidence can improve weaker models while harming stronger ones. Extensive experiments across ten million trials, twelve LLMs from four families, and eight domains—including quantum mechanics, physics, genetics, and molecular biology—confirm these predictions and reveal that evidence integration occurs late in the network as a structured sequence of steps rather than through a simple trust metric.
By Sebastien Kawada, Manolis Kellis
arXiv:2602. 06448v2 Announce Type: replace-cross Abstract: Large Language Model (LLM)-based scientific agents have accelerated scientific discovery, yet they often suffer from significant inefficiencies due to adherence to fixed initial priors.
By Yingming Pu, Tao Lin, Hongyu Chen
arXiv:2608. 06128v1 Announce Type: new Abstract: Search agents extend large language models beyond static parametric memory by enabling them to acquire and use ex ternal evidence during multi-step reasoning.
By Xingyu Guo, Wei Chen, Linlin Yang, Baochang Zhang
arXiv:2608. 15669v1 Announce Type: new Abstract: Scientific discovery often involves optimising expensive-to-evaluate objectives over vast, structured, and open-ended hypothesis spaces, such as molecules, protein sequences, and computer programs.
By Zhongwei Yu, Yan Song, Xue Yan, Anjie Liu, Xingyu Lu, Yihang Chen, Huichi Zhou, Siyuan Guo, Luoyang Sun, Sihan Chen, Xiangning Yu, Jun Wang
arXiv:2606. 11851v1 Announce Type: new Abstract: Open-ended scientific discovery asks agents to move beyond executing analyses for predefined questions.
By Jiayao Chen, Shi Liu, Linyi Yang
arXiv:2606. 04751v1 Announce Type: new Abstract: Large language models (LLMs) are increasingly deployed as autonomous agents in scientific tasks.
By Leonardo Bertolazzi, Katya Tentori, Raffaella Bernardi
arXiv:2609.01526v1 Announce Type: new
Abstract: Scientific agents must learn not only how to reason, but also what to believe. However, existing LLM agents typically express scientific hypotheses in...
By Qing Zhao, Haowei Li, Weijian Deng, Pengxu Wei, Liang Lin
The paper introduces Agentic Reasoning for Tree Search (ARTS), a method that uses a reasoning language model to navigate the hypothesis‑experiment space in scientific discovery. Unlike traditional approaches that conflate hypothesis quality with execution quality and prune search logs, ARTS evaluates prior execution logs to distinguish implementation failures from poor hypotheses and selects the next hypothesis to pursue. By employing test‑time training to embed search‑tree knowledge into model weights, ARTS achieves a 15.3% relative improvement over leading algorithms on 22 benchmark tasks and enables smaller models like Qwen3‑4B to match or exceed the performance of larger closed‑source models at lower inference cost.
By Gurusha Juneja, Arnav Kumar Jain, Deepak Nathani, William Yang Wang, Xin Eric Wang
arXiv:2607. 28684v1 Announce Type: new Abstract: Existing benchmarks for scientific equation discovery are largely composed of well-known equations available in the public domain, making it difficult to determine whether a model is discovering laws from data or merely recalling answers from its training corpus.
By Zhan'ao Yao, Liang Yin, Zhihao Gao, Boxuan Zhang, Xiaoyu Wu, Linjing Li, Rongyan Wang, Tingwei Chen, Youwei Wang, Xiaolin Zhao, Jiahui Shi, Jianjun Liu
arXiv:2607. 03426v1 Announce Type: cross Abstract: Large language models (LLMs) exhibit strong reasoning and world-knowledge capabilities, yet often struggle to gather information effectively across the multi-turn interactions required in sequential decision-making settings.
By Jakob Hartmann, James Harvey, Jhonathan Navott, Erik Y. Wang, Luckeciano C. Melo, Flaviu Cipcigan, Cheng Zhang, Alessandro Abate
arXiv:2607. 01131v1 Announce Type: cross Abstract: Autonomous scientific discovery systems offer the potential to accelerate research by automating the process of hypothesis generation and validation.
By Bingchen Zhao, Sara Beery, Oisin Mac Aodha