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arXiv:2502. 18864v2 Announce Type: replace Abstract: Scientific discovery is driven by scientists generating novel hypotheses for complex problems that undergo rigorous experimental validation.
The paper introduces CellForge, a team of autonomous agents that can autonomously generate, train, and validate predictive models for single‑cell perturbation data across transcriptomic, epigenomic, and proteomic contexts. By surveying literature, parsing data, and engaging in critic‑mediated discussions among specialized agents, CellForge produces end‑to‑end model architectures and code without human specification, achieving performance competitive with state‑of‑the‑art hand‑crafted methods. Human evaluators found CellForge’s research plans to be more scientifically sound and innovative than those produced by single large language models or deep‑research systems.
arXiv:2602. 02905v2 Announce Type: replace Abstract: Autonomous agents powered by large language models (LLMs) promise to accelerate scientific discovery end-to-end, but rigorously evaluating their capacity for verifiable discovery remains a central challenge.
arXiv:2609.07611v1 Announce Type: new Abstract: Scientific ideation is the capacity to formulate novel and testable hypotheses from scientific evidence, and autonomous AI scientists depend on it. Exi...
The paper introduces SEER‑Repro, a benchmark of 20 SEER‑based studies with data and resources for reproduction. An LLM agent reproduces 77.4% of 2,190 atomic claims and provides executable baselines. An agentic analysis pipeline then tests robustness by identifying analytical choices, proposing alternatives, and rerunning analyses, flagging potentially consequential choices in 9.5% of fully reproduced findings for expert review.
arXiv:2609.33357v2 Announce Type: replace Abstract: Reliable automated research requires agents to vet data, verify analyses, and generate hypotheses grounded in trustworthy evidence, potentially red...