Framework for Grounding Healthcare LLMs in a Causal Knowledge Graph: A Cardiovascular Example Pilot
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arXiv:2608. 15382v1 Announce Type: new Abstract: Large language models (LLMs) are increasingly proposed for healthcare decision support, but their evaluations still reward single-answer accuracy rather than reasoning about interventions, mechanisms, harms, evidence, and uncertainty.
arXiv:2606. 29876v1 Announce Type: cross Abstract: Modern large language models (LLMs) reach 60-70% diagnostic accuracy on complex clinical case benchmarks, but accuracy alone cannot distinguish stable clinically-grounded reasoning from pattern matching.
arXiv:2608. 02877v1 Announce Type: new Abstract: Causal discovery recovers directed structure from observational data and is increasingly used in clinical settings to support mechanism reasoning and fairness audits of predictive models.
The paper introduces Clinical Graph-JEPA, a framework for building and refining predictive patient-state knowledge graphs from clinical records. It combines multi-agent relation proposal, ontology-aware normalization, deterministic evidence scoring, and JEPA-based latent refinement to construct evidence-scored graphs from MIMIC-IV data and recover missing clinical relations. Experiments show that injecting discharge-note representations into note-grounded entities boosts leave-one-out MRR by 31% relative improvement.
arXiv:2607. 21859v2 Announce Type: replace Abstract: Constructing causal directed acyclic graphs (DAGs) is a core step in biomedical causal analysis, yet it remains a largely manual process.
arXiv:2608.10725v2 Announce Type: replace Abstract: Large language models (LLMs) often rely on shortcuts rather than systematic reasoning, raising safety concerns in medical applications. Allowing mo...