arXiv AI By Yi-han Sheu, Michael R. Steigman, Yu Zhou, Bo Wang, Fan-Yu Yen, Jordan W. Smoller

EviDAG: Auditable Causal DAG Authoring with Biomedical Literature

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arXiv:2607. 21859v2 Announce Type: replace Abstract: Constructing causal directed acyclic graphs (DAGs) is a core step in biomedical causal analysis, yet it remains a largely manual process.

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arXiv AI
Jul 28

Structure Over Scale: Schema-Constrained Causal Graphs for RAG

arXiv:2607. 22592v1 Announce Type: new Abstract: Graph-based retrieval-augmented generation (GraphRAG) grounds answers in structured knowledge, but current systems extract entities and relationships exhaustively, producing graphs whose size and construction cost scale with corpus length rather than with the reasoning a query requires.

By Marc Saouda (Boston Consulting Group), Rajprakash Bale (Boston Consulting Group), Eren Aldis (Boston Consulting Group), Cloves Almeida (Boston Consulting Group)
arXiv AI
Sep 2

Medical Causal Hypothesis Verification with Large Language Models

The paper "Medical Causal Hypothesis Verification with Large Language Models" reports a small-scale study evaluating eight LLMs on 17 medical causal hypotheses. The authors introduce an evaluation framework and annotate 1,067 evidence points across six criteria, using nine metrics to assess performance. Results show that while LLMs have strong recall, they frequently fail to provide valid scientific articles, evidence, or reject unsupported hypotheses, revealing a critical limitation for their use in healthcare.

By Safiyyah Ahmed, Abrar Ansari, Md Aminul Islam, Elena Zheleva
arXiv AI
Sep 10

Building evidence-based knowledge bases from full-text literature for disease-specific biomedical reasoning

EvidenceNet is a disease‑specific dataset that transforms full‑text biomedical literature into structured evidence records and graph representations, preserving study design, provenance, and quantitative support. Using an LLM‑assisted pipeline, it extracts experimentally grounded findings, normalizes entities, scores evidence quality, and links related records via typed semantic relations. The released subsets—EvidenceNet‑HCC and EvidenceNet‑CRC—contain thousands of evidence records and richly connected graphs, with high extraction and relation‑type accuracy, enabling retrieval‑augmented question answering and graph‑based tasks such as link prediction and target prioritization.

By Chang Zong, Jinyu Chen, Sicheng Lv, Si-tu Xue, Huilin Zheng, Jian Wan, Lei Zhang
arXiv Computation and Language
Sep 23

Quantitative Evidence Mining for Plausibility-Aware Biomedical AI: A Narrative Review and Conceptual Framework

The article proposes a framework called quantitative evidence mining to transform biomedical findings into structured, context-rich evidence units. It outlines core elements such as claim, measured entity, value, comparator, population, conditions, temporal context, uncertainty, provenance, validation, and expert review. The authors present an eight-stage reference architecture and emphasize that plausibility should remain multidimensional rather than collapsed into a single truth label, linking extraction to evidence synthesis for applications like clinical trials, biomarker research, and knowledge-graph construction.

By Negin Sadat Babaiha, Stefan Geissler, Marie-Christine Simon, Martin Hofmann-Apitius, Marc Jacobs