Do Synthetic Personas Predict Real Audience Response? A Sim-to-Real Study Where a No-Persona Baseline Beats Persona-Based Copy Simulation

The study evaluates whether large language models (LLMs) used as synthetic personas can predict real audience responses to marketing copy. Using thousands of headline A/B tests from the Upworthy Research Archive, the authors compare a ten-persona panel grounded in real audience demographics to a no-persona zero‑shot baseline that asks the model for a typical reader’s click likelihood. Results show that the no‑persona baseline outperforms the persona‑based approach, with higher predictive validity and top‑1 accuracy, indicating that forcing the model to role‑play specific personas introduces bias and noise.

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