arXiv AI By Tong Ding, Caiwei Tian, Dongmin Bang, Ming Y. Lu, Sophia J. Wagner, Andrew Zhang, Rowland Pettit, Long Phi Le, Faisal Mahmood

Discrete Neural Interlingua for Ontology-Agnostic EHR Modeling

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The paper introduces MEDIATOR, a discrete, ontology‑agnostic tokenizer that maps any clinical concept—whether encoded, synonymous, or free‑text—into a shared vector‑quantized codebook. By collapsing equivalent expressions and organizing distinct concepts in a medically meaningful space, MEDIATOR serves as the token interface for an EHR Transformer, boosting mean AUPRC by 4.0 points on 20 MIMIC‑III tasks and 8.6 points in zero‑shot transfer to 14 eICU tasks, while enabling full event coverage and transferable attribution across hospitals.

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