arXiv AI By Aarzoo Dhiman, Farzana Haque, Kartikae Grover, Lydia Brian Smith, William Stephen Jones

Development and Feasibility Evaluation of an Edge AI as Medical Device System for Breast Cancer Multidisciplinary Team Meetings

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arXiv AI
Sep 2

Towards AI-Assisted Clinical Trial Matching: Practical Considerations, Multicenter Evaluation, and Real-World Deployment

arXiv:2609.01202v1 Announce Type: cross Abstract: Clinical trials are essential for advancing cancer care and drug development, but many fail because of insufficient patient enrollment. While there i...

By Yin Fang, Qiao Jin, Shubo Tian, Lauren He, Maya Geer, Noor Naffakh, Ryan Huu-Tuan Nguyen, Zifeng Wang, Jimeng Sun, Charalampos S. Floudas, James L. Gulley, Kamilia Moalem, Catarina Martins Maia, Amanda Nottke, Juan W. Valle, Melinda Bachini, Lourdes Rocha-Nussbaum, Kari Ramage, Nikita Curry, Megan Barnes, Mandy Mansaray, Darlene Gabeau, Craig E. Grossman, Heath Skinner, Michael Burczynski, NIH-TrialBench Consortium, Zhiyong Lu
arXiv AI
Sep 25

CRISS: A Retrieval-Augmented AI Chatbot for Assisting Cancer Registrars

CRISS is a retrieval‑augmented generation chatbot designed to aid cancer registrars by providing rapid, citation‑supported answers to complex coding and staging questions. It uses a domain‑specific knowledge base of national registry standards, indexed as dense embeddings, to retrieve relevant passages that ground responses generated by a large language model. In evaluations, RAG configurations consistently outperformed non‑RAG baselines across easy, medium, and hard questions, achieving higher grounding and semantic similarity scores while maintaining human oversight for final decisions.

By Vani Seth, Mohammad Beheshti, Anirudh Kambhampati, Vishwa Bhayani, Lucinda Ham, Prasad Calyam, Iris Zachary
arXiv AI
Jul 15

First, do NOHARM: a medical safety benchmark and randomized study of physician and AI teaming on clinical consultations

arXiv:2512. 01241v4 Announce Type: replace-cross Abstract: Large language models (LLMs) and medical AI tools are routinely used by physicians and patients for medical advice, yet their clinical safety profiles remain poorly characterized.

By David Wu, Fateme Nateghi Haredasht, Saloni Kumar Maharaj, Priyank Jain, Jessica Tran, Matthew Gwiazdon, Arjun Rustagi, Jenelle Jindal, Jacob M. Koshy, Vinay Kadiyala, Anup Agarwal, Bassman Tappuni, Brianna French, Sirus Jesudasen, Christopher V. Cosgriff, Rebanta Chakraborty, Jillian Caldwell, Susan Ziolkowski, David J. Iberri, Robert Diep, Rahul S. Dalal, Kira L. Newman, Kristin Galetta, J. Carl Pallais, Nancy Wei, Kathleen M. Buchheit, David I. Hong, Vartan Pahalyants, Ernest Y. Lee, Allen Shih, Tamara B. Kaplan, Vishnu Ravi, Sarita Khemani, Thomas A. Buckley, April S. Liang, Daniel Shirvani, Advait Patil, Nicholas Marshall, Kanav Chopra, Joel Koh, Adi Badhwar, Anastasia Perez, Austin J. Schoeffler, Mahbuba Tusty, Chase M. Walton, Liam G. McCoy, David J. H. Wu, Yingjie Weng, Sumant Ranji, Kevin Schulman, Nigam H. Shah, Jason Hom, Arnold Milstein, Arjun K. Manrai, Adam Rodman, Jonathan H. Chen, Ethan Goh
arXiv AI
Sep 1

From Analytics to Tumor Boards: An Evidence-Linked Multi-Agent Workflow for Oncology Feature Extraction

arXiv:2608.28974v1 Announce Type: new Abstract: Clinically relevant oncology information is distributed across heterogeneous, longitudinal documentation, creating substantial abstraction burden and r...

By Daniel Kang, Michelle Hu, Soorya Ram Shimgekar, Shayan Vassef, Yufan Wang, Anit Kumar Sahu, Munmun De Choudhury, Vedant Das Swain, Christian Poellabauer, Li Yan Khor, Koustuv Saha, Robert Wojciechowski, Elliot Kidd, Piyum Zonooz, Navin Kumar
arXiv AI
Sep 15

ClinAgent: A ReAct-Based Agent for Conversational Access to Clinical Trial Information

ClinAgent is a conversational system that uses a ReAct-based LLM agent to retrieve and synthesize clinical trial information from multiple sources such as ClinicalTrials.gov, PubMed, and a local dataset. The agent iteratively reasons over user queries, selects appropriate tools, and refines its actions to provide grounded, up-to-date responses in natural language across multi-turn interactions. Evaluation across three phases shows that DeepSeek (thinking mode) excels in planning quality while Gemini 3.0 Flash delivers the highest overall performance and expert ratings, demonstrating the promise of agentic AI for improving clinical trial data access.

By Antonino Vaccarella, Riccardo Cantini, Domenico Talia, Paolo Trunfio, Marianna Talia, Rosamaria Lappano, Marcello Maggiolini
arXiv AI
Jul 13

Evaluating Retrieval-Augmented Generation vs. Long-Context Input for Clinical Reasoning over EHRs

arXiv:2508. 14817v2 Announce Type: replace-cross Abstract: Objective: To evaluate whether retrieval-augmented generation (RAG) can serve as an efficient alternative to long-context prompting for clinical reasoning over electronic health records (EHRs).

By Skatje Myers, Dmitriy Dligach, Timothy A. Miller, Samantha Barr, James Landefeld, Yanjun Gao, Matthew Churpek, Anoop Mayampurath, Majid Afshar