arXiv AI By Seyed Mahmoud Sajjadi Mohammadabadi

BioSync: Transformer-Based Cross-Modal Fusion for a Multimodal Physiological Digital Biomarker

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BioSync is a transformer-based model that fuses cardiac, neural, behavioral, and speech data from wearables and mobile devices into a continuous composite digital biomarker called the BioSync Index (BSI). The architecture uses multi-head self-attention on modality tokens and a linear branch for feature concatenation, inspired by latent-variable measurement theory. Evaluations on synthetic cohorts for cognitive decline and metabolic-autonomic conditions show BioSync achieving AUCs of 0.928 and 0.764 accuracy/F1 of 0.766, outperforming simple concatenation and other fusion strategies in most corruption scenarios.

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