HyGRAIL is a framework for discovering scientific hypotheses in incomplete knowledge graphs by combining a graph neural network (GNN) triage with large language model (LLM) review. The GNN scores candidate hypotheses and routes only ambiguous cases to the LLM, which receives structured evidence from the graph converted into natural language. Experiments on MatKG show HyGRAIL achieves the highest F1 score, improves over baselines, and cuts LLM calls by over 54%.
By Yihang Sun, Zhihan Zhu, Zhiyuan Jiang, Jingyi Ge, Zixuan Li, Jiaxuan You
Scientific knowledge graphs organize entities and relations extracted from scientific literature, but they remain inherently incomplete. Missing typed links in such graphs can therefore represent plau...
The paper introduces BAR, a Budget‑Aware LLM Reasoning framework that enhances post‑discharge risk prediction by integrating external medical knowledge graphs (KGs). BAR refines KGs into disease‑specific evidence graphs with support scores and provenance, then uses an LLM to plan, navigate, and verify evidence within a patient‑specific budget. Experiments on MIMIC‑III and MIMIC‑IV across eight diseases show BAR improves AUPRC by 3.4 points, raises citation precision from 59.8% to 77.9%, and uses only 62‑65% of the allotted budget.
By Chen Chen, Dongjie Wang, Mei Liu, Zijun Yao
arXiv:2608.30393v1 Announce Type: new
Abstract: Biomedical artificial intelligence (AI) systems increasingly extract, organize, and reuse scientific claims from literature, clinical trials, and regul...
By Negin Sadat Babaiha, Stefan Geissler, Marie-Christine Simon, Martin Hofmann-Apitius, Marc Jacobs
The paper proposes a layered verification approach for argument graphs generated by large language models (LLMs). It suggests starting with deterministic checks, then using solver-based methods, followed by LLM reviews, and resorting to debate only when uncertainty remains, reserving human judgment for cases no other instrument can resolve. A study on human-annotated graphs with injected defects shows that while LLM reviewers can detect structural issues with high recall, they also produce false positives, exhibit inconsistent verdicts, and are slower than exact checks, underscoring the need for deterministic verification gates.
By Jakub B\k{a}ba, Jaros{\l}aw A. Chudziak
arXiv:2511. 03217v2 Announce Type: replace-cross Abstract: Large language models (LLMs) excel in generating fluent utterances but can lack reliable grounding in verified information.
By Shaghayegh Kolli, Richard Rosenbaum, Timo Cavelius, Lasse Strothe, Andrii Lata, Jana Diesner