arXiv AI By Kaela Kokkas, Hairong Wang, Richard Klein, Nazir A. Ismail, Natalie Irwin, Mohammad Z. Moonsamy, Kubendran Naidoo, Jeremy Nel, Ekene E. Nweke, Raveen Parboosing, Emmanuel K. Sekyi, Rebecca T. van Dorsten, Bruce A. Bassett, Robert F. Breiman

Artificial Intelligence Can Match Domain Experts in Evidence Extraction and Critical Appraisal of Microbial Oncogenesis Research Publications

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arXiv:2608. 07250v1 Announce Type: cross Abstract: Confirmed oncogenic microbes contribute significantly to cancer burden.

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arXiv AI
Jun 2

Med-V1: Small Language Models for Zero-shot and Scalable Biomedical Evidence Attribution

arXiv:2603. 05308v3 Announce Type: replace-cross Abstract: Assessing whether an article supports an assertion is essential for hallucination detection and claim verification.

By Qiao Jin, Yin Fang, Lauren He, Yifan Yang, Guangzhi Xiong, Zhizheng Wang, Nicholas Wan, Joey Chan, Donald C. Comeau, Robert Leaman, Charalampos S. Floudas, Aidong Zhang, Michael F. Chiang, Yifan Peng, Zhiyong Lu
arXiv AI
Sep 7

A Semantic Model of Genetic Evidence: A Step Toward Bridging the Basic-Science-Clinic Gap

The article presents a new semantic model for representing scientific evidence, specifically tailored to genetics, that extends existing standards by adding fine‑grained, domain‑specific structure. It aligns with FHIR Evidence and SEPIO, incorporates a compact vocabulary validated by SHACL, and was tested in a human‑AI annotation pilot on six genetics papers, producing 28 evidence items and 95 source‑anchored assertions. The authors argue that this model advances trustworthy, AI‑ready infrastructure for variant interpretation by providing a reference data model and validation schema for genetic evidence.

By Michael Bouzinier, Dmitry Etin
arXiv AI
2d ago

OpenMTB-Audit: Exposing Over-Refusal and Clinical Expert Perspectives in LLM-Based Molecular Tumor Board Safety Evaluation

OpenMTB‑Audit is an open‑source benchmark that tests large language models on 500 synthetic non‑small cell lung cancer cases, covering five adversarial error categories and four safety labels: Supported, Partially Supported, Unsupported, and Insufficient Information. The study found that all eight tested LLMs over‑refused Partially Supported recommendations, collapsing labels to achieve high safety scores. A deterministic seven‑module framework, MTB‑AuditAgent, was introduced to reduce over‑refusal to 6.7% and reach 91.2% accuracy, while an oncologist annotation study highlighted disagreement around the boundary between information sufficiency and treatment optimization.

By Negin Ashrafi, Jia Luo, Stacey M. Frumm, Roxana Daneshjou
arXiv Computation and Language
Sep 23

Quantitative Evidence Mining for Plausibility-Aware Biomedical AI: A Narrative Review and Conceptual Framework

The article proposes a framework called quantitative evidence mining to transform biomedical findings into structured, context-rich evidence units. It outlines core elements such as claim, measured entity, value, comparator, population, conditions, temporal context, uncertainty, provenance, validation, and expert review. The authors present an eight-stage reference architecture and emphasize that plausibility should remain multidimensional rather than collapsed into a single truth label, linking extraction to evidence synthesis for applications like clinical trials, biomarker research, and knowledge-graph construction.

By Negin Sadat Babaiha, Stefan Geissler, Marie-Christine Simon, Martin Hofmann-Apitius, Marc Jacobs