arXiv Statistics ML By Hanqing Li, Yaroslav Golub, Xuewen Lu

Adaptive mixture variational inference for spike-and-slab regression

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The paper introduces an adaptive fitting procedure for mixtures of product distributions in Gaussian regression with a spike‑and‑slab prior, directly minimizing reverse Kullback‑Leibler divergence on inclusion indicators and active coefficients. This method jointly refines component parameters and weights as the mixture grows, avoiding extra divergence penalties on unused latent coefficients. Empirical results on 250 simulated datasets show that mixtures reduce errors in inclusion probabilities, grouped support probabilities, and coefficient covariance compared to multistart mean‑field approaches, and that direct joint refinement outperforms augmented or restricted refinement at fixed mixture size.

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