arXiv Computer Vision
2d ago

A Visual Grounding Benchmark for Retinal OCT with Multimodal Large Language Models

The paper introduces RetinaGroundBench, a new benchmark for visual grounding of retinal OCT images, featuring 815 B-scans annotated with 4,537 bounding boxes for 13 biomarkers across 8 diseases. It evaluates 27 multimodal large language models (MLLMs) and finds that visual grounding is largely unsolved, with the best model achieving only a macro F1 of 23.7%. The authors also present RetGrounder, an 8‑B parameter MLLM fine‑tuned for OCT, which raises grounding F1 to 33.9%, a 43% relative improvement.

By Ronald Fecso, Jos\'e Morano, Botond Fazekas, Paul Widmann-Sedlnitzky, Dorota Himel, Laetita Hinterhuber, Virginia Mares, Andreas Pollreisz, Hrvoje Bogunovi\'c
arXiv AI
Sep 1

Co-Annotator: Expert-Distilled ViT and VLM for Visual and Documentation Guidance in Age-Related Macular Degeneration

Co-Annotator is a clinical AI system that distills expert gaze and dictation into two guidance components: a gaze‑aligned Vision Transformer that highlights fixation‑aligned areas of interest (AOIs) and an ontology‑bounded vision‑language model that pre‑fills editable biomarker summaries for retinal OCT. In controlled studies, each modality independently improved diagnostic accuracy and biomarker generation, and when combined across two academic institutions, the system increased correct diagnoses per minute by 40% and reduced comment editing time by 67% without compromising accuracy.

By Ziheng "Leo" Li, Benjamin Freeman, Akshay Raman, Kavin Aravindhan Rajkumar, Xinxin Fang, Rishabh Srivastava, Steven Feiner, Kaveri A. Thakoor
arXiv AI
Jun 8

MMBU: A Massive Multi-modal Biomedical Understanding Benchmark to Probe the Perception Capabilities of Vision-Language Models

arXiv:2606. 06696v1 Announce Type: cross Abstract: Vision and language models (VLMs) hold immense promise to transform biomedical imaging workflows, from detecting lesions in chest X-rays to profiling cellular features in microscopy.

By Ryan D'Cunha, Alejandro Lozano, Xiaoxiao Sun, Daniel Vela Jarquin, Min Woo Sun, Josiah Aklilu, James Burgess, Yuhui Zhang, Ryan Nayebi, Paola Avila, Robayo, Jin Ye, Ming Hu, Zhongying Deng, Junjun He, Xin Chen, Yue Yao, Robert Tibshirani, Jeffrey J. Nirschl, Serena Yeung-Levy
arXiv AI
Aug 28

From Reasoning to Pixels: Grounded Medical Multimodal LLMs for VQA and Segmentation

The paper introduces MedREAL, a unified framework that aligns linguistic reasoning with spatial grounding for medical visual question answering and segmentation. MedREAL employs Seg Anchored Reasoning Pooling (SARP) to extract semantic evidence from segmentation tokens and a Reasoning-to-Visual (R2V) fusion mechanism to integrate these features into a segmentation pipeline. Using the newly created MedRAVS-13K dataset, MedREAL achieves superior performance, reporting 68.49% gIoU and 70.47% cIoU, and generates evidence masks that consistently match textual diagnoses.

By Haowen Gu, Gensheng Pei, Junzhu Mao, Qiong Wang, Mingwu Ren, Yazhou Yao