OpenAI Blog

Accelerating the development of life-saving treatments

Accelerating the development of life-saving treatments.

arXiv AI
Sep 7

Model Retirement Creates Reproducibility Risk in Biomedical AI Publications

The study examined biomedical research articles from 2022 to March 2026 that employed large language models (LLMs). It found that 42% of the most frequently used models were already retired or scheduled to retire within two years of publication, with a median retirement interval of 538 days. This high rate of model deprecation threatens the reproducibility of biomedical AI research.

By Nathan Wolfrath, Meghan Conroy, Thomas Kosten, Dave Bell, Bhabishya Neupane, Jonah Kindel, Anjishnu Banerjee, Priya Deshpande, Bradley Taylor, Anai N. Kothari
arXiv Machine Learning
Jul 24

A Diffusion-Model Subpopulation Digital Twin for Mobile Health Deployment: A Case Study on the HeartSteps Intervention

arXiv:2607. 21403v1 Announce Type: new Abstract: Mobile-health interventions increasingly use online learning and decision making algorithms to personalize when to nudge users toward healthier behavior, but a poorly designed algorithm can burden and disengage participants.

By Ziping Xu, Yuyi Chang, Chenshun Ni, Nithin Sugavanam, Asim H. Gazi, Pedja Klasnja, Emre Ertin, Susan A. Murphy