arXiv Computation and Language

Domain-Specific Constitutional AI: Enhancing Safety in LLM-Powered Mental Health Chatbots

The paper introduces a domain‑specific Constitutional AI framework designed to improve safety in large‑language‑model‑powered mental health chatbots. It highlights the unique risks of mental‑health applications—such as misdiagnosis, symptom exacerbation, and self‑harm—and argues that general AI safeguards are insufficient for these sensitive contexts. The authors propose training models with mental‑health‑specific principles to ensure accurate crisis intervention, adherence to therapeutic guidelines, and robust handling of nuanced, vulnerable dialogues.

arXiv AI
Aug 24

When Vocabulary Comprehension Fails Clinical Reasoning: Evaluating Therapy Bots' Safety Risks for Generation Alpha

The paper evaluates the safety of conversational AI therapy bots for Generation Alpha, revealing that while these models understand 76‑82% of youth‑specific vocabulary, they correctly assess clinical risk only 64‑72% of the time, creating a significant vocabulary‑comprehension gap. Six failure patterns—such as sarcasm masking, minimization acceptance, and semantic drift—were identified, with compounded errors leading to a 94% miss rate when three or more patterns co‑occur. The authors estimate 146,880 missed crises annually and recommend mandatory human‑in‑the‑loop systems, quarterly youth‑specific validation, transparent performance disclosure, and regulatory oversight for youth‑facing mental health AI.

By Manisha Mehta, Virendra Mehta
arXiv Computation and Language
Sep 23

From Pattern Recognizers to Personalized Companions: A Survey of Large Language Models in Mental Health

The article surveys how large language models (LLMs) are being applied to mental health, outlining a three‑phase evolution: Phase I uses LLMs as passive information tools and pattern recognizers for assessment; Phase II employs them as empathetic conversationalists for stateless, in‑the‑moment interactions; Phase III aims to create longitudinal, personalized companions that act as stateful cognitive agents. It systematically reviews core technologies, agent architectures (Profile, Memory, Reasoning, Planning), and the datasets and benchmarks that support this progression, offering a coherent narrative and roadmap for future research. The survey also provides a curated resource list at https://github.com/Emo-gml/Awesome-Mental-Health-LLMs.

By He Hu, Yucheng Zhou, Qianning Wang, Yingjian Zou, Chiyuan Ma, Juzheng Si, Jianzhuang Liu, Zitong Yu, Laizhong Cui, Fei Ma, Qi Tian
arXiv AI
Aug 28

A Safety-Gated Multimodal AI Backend for Mental-Health Support: Hierarchical State Representation, Conservative Risk Fusion, and Controlled Generation in Anian

Anian is a safety‑gated multimodal AI backend designed for perinatal mental‑health support and mindfulness‑intervention routing. It maps user input into a four‑layer hierarchical state representation—emotion, psychosocial constructs, safety risk, and intervention routes—then fuses local and external risk signals to decide whether to generate AI responses or provide fixed safety content. Prototype evaluation on large public corpora showed high classification performance and perfect high‑risk recall in a controlled stress test, though clinical validity remains unestablished.

By Lei Wang, Xiao Wang, Lei Li
arXiv AI
5d ago

PromptSense: Sentiment-Aware Mental Health Chatbot with Dynamic Prompting

PromptSense introduces a sentiment‑aware mental health chatbot that incorporates sentiment and depression analysis with rule‑based filtering before model inference. By dynamically constructing prompts from emotional and risk insights, the system enhances contextual relevance, empathy, and safety of responses. Experiments across four model strategies and two prompt variants show that the engineered prompts outperform DSFT and RLAIF by 1.8% and 1.1% on qualitative metrics and toxicity assessments.

By Sugi Lee, Jianlong Zhou, Jing sUN
arXiv Computation and Language
Aug 24

Trust Stack for Mental Health AI: A Survey of Calibration across Human, Interaction, and AI Layers

The paper surveys 61 studies on mental‑health AI and identifies a misalignment in how trust is evaluated across disciplines. It proposes a three‑layer framework—human‑oriented, interaction‑oriented, and AI‑oriented trust—and maps stakeholder perspectives onto these layers. The authors argue that future research should focus on calibrating human trust to actual interaction and AI trustworthiness rather than merely maximizing perceived trust.

By Xin Sun, Yue Su, Yifan Mo, Qingyu Meng, Yuxuan Li, Min Chen, Mengyuan Zhang, Saku Sugawara, Charlotte Gerritsen, Sander L. Koole, Koen Hindriks, Jiahuan Pei
arXiv AI
22h ago

TherapyGym: Evaluating and Aligning Clinical Fidelity and Safety in Therapy Chatbots

arXiv:2603.18008v2 Announce Type: replace-cross Abstract: Large language models (LLMs) are increasingly used for mental-health support; yet prevailing evaluation methods--fluency metrics, preference...

By Fangrui Huang, Souhad Chbeir, Arpandeep Khatua, Sheng Wang, Sijun Tan, Kenan Ye, Lily Bailey, Merryn Daniel, Ryan Louie, Sanmi Koyejo, Ehsan Adeli
arXiv Computation and Language
Oct 16

MindEval2: Clinically Grounded Patients and Rubrics for Evaluating Language Models in Mental Health Support

MindEval2 is a new evaluation framework for AI chatbots in mental health support, comprising Mental Health Quality Rubrics (MHQR) and the MindSim patient simulation harness. MHQR, developed with PhD-level psychologists, provides explicit, actionable criteria for assessing response quality, while MindSim offers realistic, longitudinal patient interactions with a memory component. The study evaluated 18 models, finding that although surface-level quality has improved, guidance calibration remains the main failure across all models.

By John Mendon\c{c}a, Daniel Tschernutter, Jos\'e Pombal, Areti Vassilopoulos, Catarina Botelho, Ignacio Sarasua, Maya D'Eon, Nuno Guerreiro, Ricardo Rei