arXiv Machine Learning

Disentangling Acoustic Cues in Alzheimer's Pathology and Perception: The Roles of Language and Gender

arXiv:2607. 23977v1 Announce Type: cross Abstract: Acoustic biomarkers show promise for detecting Alzheimer's Disease (AD), yet whether the cues driving diagnostic AI align with those salient to human listeners is underexplored across languages and genders, where pathological markers and perceptual strategies differ.

arXiv Machine Learning
1d ago

Beyond Decodability: Do Acoustic Factors Drive Predictions in Speech-Based Alzheimer's Assessment?

The study investigates whether acoustic factors encoded in pretrained self‑supervised learning (SSL) models can systematically influence predictions in speech‑based Alzheimer's disease (AD) assessment. Using the ADReSSo dataset and three large SSL backbones, the authors applied controlled noise and reverberation interventions to various audio segments and combined layer‑wise decoding, input‑ and representation‑space interventions, and geometric alignment analysis. The results demonstrate that such acoustic interventions alter AD predictions across all models, with noise producing the strongest effect, and that these effects are structured relative to the classifier’s decision direction and reproducible on a held‑out test set.

By Serli Kopar, Alkis Koudounas, Roshan P. Rane, Sam Gijsen, Paula A. Perez-Toro, Kerstin Ritter
arXiv Computation and Language
6d ago

Why Alzheimer's Speech Screening Fails to Generalize: Bridging the Deployment Gap via Cross-Corpus Evidence Anchoring

The paper examines why speech‑based screening for Alzheimer’s disease fails to generalize across different languages, tasks, and recording protocols. Using a leave‑one‑corpus‑out evaluation on four datasets, it finds that 59 of 70 interpretable speech features show conflicting patterns between healthy controls and cognitive risk groups, with pause, silence, and speech rate being highly protocol‑sensitive. The authors propose a fusion method that combines XLM‑R text baseline scores with evidence anchors, improving mean speaker AUC to 0.785 and worst‑case AUC to 0.615, and emphasize the importance of auditing feature transferability and reporting worst‑case domain robustness.

By Zijian Lu, Sizhe Liu, Yin Zhang, Jixuan Deng, Xinrong Lin, Xinchen Yuan, Chicheng Jin, Yiping Zuo, Yuanchao Li
arXiv Machine Learning
Sep 16

BenSParX: A Robust Explainable Machine Learning Framework for Parkinson's Disease Detection from Bengali Conversational Speech

BenSparX introduces the first Bengali conversational speech dataset for Parkinson’s disease detection and pairs it with a robust, explainable machine learning framework. The framework uses diverse acoustic features, systematic feature selection, and advanced classifiers, achieving 95.67% accuracy, 95.62% F1, and 0.990 AUC. SHAP analysis is employed to explain feature contributions, and the model outperforms state‑of‑the‑art methods on other language datasets.

By Riad Hossain, Muhammad Ashad Kabir, Arat Ibne Golam Mowla, Animesh Chandra Roy, Ranjit Kumar Ghosh
arXiv AI
Sep 2

Cleaner Speech, Weaker Generalization: Revisiting Pitt-Derived Benchmarks for Alzheimer's Disease Detection

The study examines how speech preprocessing—such as enhancement, sample selection, and demographic balancing—affects Alzheimer’s disease detection models that use the Pitt Corpus. Experiments reveal that while speech‑enhanced datasets boost in‑domain accuracy, they diminish cross‑dataset robustness and introduce class imbalance and prediction shifts, even when training and testing enhancements are matched. Large audio‑language models show similar sensitivity, indicating that cleaner speech does not guarantee better real‑world performance.

By Luqi Sun, Shreeram Suresh Chandra, Lin Zhang, You-Jin Li, Brian MacWhinney, Yu Tsao, Emily Mower Provost, Berrak Sisman
arXiv Machine Learning
Aug 27

Behind the [MASK]: Disentangling Representation and Faithfulness in DAPF-Based Dementia Detection

The paper investigates the interpretability of Domain-Adapted Prompt-based Fine-tuning (DAPF) models for dementia detection from spoken language. Using probing and analysis techniques, the authors find that DAPF achieves strong overall performance (accuracy = 0.83, macro‑F1 = 0.83) and that the diagnosis is most recoverable from its [MASK] representation. However, token‑level explanations derived from DAPF are largely driven by language‑task vocabulary, discourse markers, and transcription artifacts, and perturbation tests reveal weak or negative effects, indicating that the masked‑token interface captures diagnosis information without providing faithful token‑level explanations.

By Pardis Ranjbar-Noiey, Natalie Parde
arXiv Computation and Language
Sep 10

False positive bias in AI-powered speech-based cognitive screening for multilingual English speakers in the UK

arXiv:2602.13047v2 Announce Type: replace Abstract: Conversational speech reveals early signs of cognitive decline, including dementia and mild cognitive impairment (MCI). AI models show promise for...

By Madhurananda Pahar, Caitlin Illingworth, Dorota Braun, Bahman Mirheidari, Lise Sproson, Daniel Blackburn, Heidi Christensen