La Agente ’Optima is an agentic framework that builds and manages Bayesian optimization campaigns for self‑driving laboratories, separating large language model reasoning from campaign execution. It maintains a persistent optimization state, allowing consistent repetitive loops and auditable decisions, and only returns control to the agent when interpretation or revision is needed. In tests on digital discovery tasks and physical platforms, it corrected measurement failures, improved yields, and recommended formulation changes, outperforming human‑directed campaigns in cost and material usage.
By Marcel M\"uller, Jiaru Bai, Willi Gottstein, Abhijoy Mandal, Mohammad Nazeri, Elia Savino, Yanlin Fang, Sujoy Das, Sergio Pablo Garc\'ia Carrillo, Yeonghun Kang, Juan B. P\'erez-S\'anchez, Simone Pilon, Martin Fitzner, Timothy No\"el, Frank Gu, Varinia Bernales, Al\'an Aspuru-Guzik
arXiv:2607. 11959v1 Announce Type: new Abstract: Greenhouse reinforcement learning can test climate-control ideas at a speed and scale that is difficult to achieve with crop experiments alone.
By Yuhui Bie, Guowei Xu, Yaojun Wang
arXiv:2607. 04508v1 Announce Type: new Abstract: Agentic AI-for-Science can automate ideation, planning, and analysis, but final validation still depends on real experiments.
By Kyunghoon Hur, Chihun Lee
arXiv:2610.18449v1 Announce Type: new
Abstract: AI agents for autonomous scientific discovery must decide which experiments to run under a limited budget. Most benchmarks for science agents provide f...
By Yibo Wen, Han Liu
The paper introduces Autonomous Science Bench, a benchmark for AI agents that must choose experiments under a limited budget. It features six real-world design-build-test-learn campaigns in biology, chemistry, and materials science, where agents select design batches, receive lab measurements, and iteratively refine a predictive model. Success is measured by two calibrated gates—discovery and learning—highlighting distinct agent weaknesses that overall success rates alone would mask.
arXiv:2512. 21066v4 Announce Type: replace Abstract: Explainable artificial intelligence (XAI) reveals how explanatory variables relate to a response variable, yet communicating XAI outputs to laypersons remains difficult, limiting trust in AI-based predictions.
By Tomoaki Yamaguchi, Yutong Zhou, Masahiro Ryo, Keisuke Katsura
arXiv:2610.16297v1 Announce Type: cross
Abstract: Scaling laws predict large-model performance from small experiments, but finding a reliable law itself requires costly experiments. SLDBench tests wh...
By Lingbei Meng, Rui Huang, Zhirong Shen, Jinxin Liu, Lingxiao Jing, Haorui Chen, Yaosong Du, Haowei Lin
arXiv:2606. 04261v1 Announce Type: new Abstract: Curating training data is among the most consequential yet labor-intensive parts of modern AI development: practitioners iteratively propose, implement, evaluate, and revise data policies against noisy benchmark feedback.
By Feiyang Kang, Hanze Li, Adam Nguyen, Mahavir Dabas, Jiaqi W. Ma, Frederic Sala, Dawn Song, Ruoxi Jia
The paper argues that evaluating agents as fixed models is insufficient, proposing instead to treat them as configurable systems. Using a new benchmark of four scientific tasks, the authors analyze how five configuration aspects—task information, reasoning, self‑verification, time budget, and backbone model—affect performance, noting that about 54% of outcome variance arises from run‑to‑run differences even with the same settings. The study finds that providing more task information has the strongest impact, while interactions among settings (e.g., extra time only helps with adequate information or model capability) and the choice of verification tools significantly shape agent behavior.
By Luis Wiedmann, Leander Girrbach, Cordelia Schmid, Zeynep Akata
arXiv:2608.20566v1 Announce Type: new
Abstract: AI agents extend large language models from single prompt-response interactions to long-running, goaldirected workflows that issue many model calls, in...
By Leyi Yan, Shuangning Li, Sihang Liu
arXiv:2608. 13940v1 Announce Type: new Abstract: AI research agents (AIRA) can now propose, implement, and evaluate their own machine learning experiments, but progress on frontier tasks is throttled by cost: a candidate solution can be written in minutes, whereas evaluating it can take hours to days of GPU time.
By Thomas Simon Foster, Bassel Al Omari, Tingchen Fu, Thomas Mann, Carl Domond, Lucia Cipolina-Kun, Bhavul Gauri, Muna Aghamelu, Alexander D. Goldie, Eryk Helenowski, Jean-Christophe Gagnon-Audet, Alberto Pepe, Saba Nazir, Daniel Izcovich, Noam Levi, Rishi Hazra, Karen Hambardzumyan, Nicolas Baldwin, Xian Li, Martin Josifoski, Paris Giampouras, Masoud Jalili Sabet, Anya Sims, Hela Momand, Tatiana Shavrina, Despoina Magka, Jason Weston, Yulin Wang, Anirudh Goyal, Jo\~ao Henriques, Yoram Bachrach, Emily McMilin, Jakob Nicolaus Foerster
Mimir is a physics‑grounded large language model agent designed for long‑horizon irrigation control. It operates on two timescales: a fast scale that uses a structured physical interface and deterministic simulator to validate and refine LLM proposals before execution, and a slow scale that consolidates recurrent failure patterns into persistent contextual principles. Across multiple sites, crops, and years, Mimir achieves the lowest aggregate control cost and reduces irrigation usage by about 51% compared to historical schedules, while ablation studies confirm the importance of forward simulation, verified revision, and persistent context.
By Yimeng Liu, Mi Zhang, Younsuk Dong, Zhichao Cao