arXiv:2607. 04353v1 Announce Type: cross Abstract: Hierarchical structure is common in image data, where fine-grained clusters often merge into larger, coarser semantic groups.
By Julius Riel, Vishwa Mohan Singh, Sai Anirudh Aryasomayajula, Anuun Chinbat, Hannes Leonhard, Moritz Ladenburger, Frederik Alexander, Vishisht Choudhary, Fabio Laredo, Giacomo Masserdotti, Thorben Prein, Carsten Marr, Amirhossein Kardoost
arXiv:2603. 13377v2 Announce Type: replace-cross Abstract: Representation learning has driven major advances in natural image analysis by enabling models to acquire high-level semantic features.
By Ivan Svatko, Maxime Sanchez, Ihab Bendidi, Gilles Cottrell, Auguste Genovesio
arXiv:2609.23019v1 Announce Type: cross
Abstract: Soma instance segmentation, i.e., identifying and delineating individual cell somas as distinct instances, is crucial for cellular analysis and conne...
By Mohammad Khateri, Morteza Ghahremani, Jussi Tohka, Alejandra Sierra
The paper introduces an end‑to‑end framework for detecting and classifying cells in pathology images by jointly modeling visual features and instance‑level interactions. It employs a dynamic graph construction module that builds cell graphs from learnable queries and an instance‑aware graph network that filters and reorganizes features, integrating appearance and relational evidence. Experiments on multiple staining protocols show the method surpasses existing approaches in both detection and classification accuracy.
By Ruochen Liu, Yalin Zheng, Jingxin Liu, Jianfeng Zhang, Shoujun Huang, Dexing Kong, Haofeng Li, Wei Lou
arXiv:2609.36429v1 Announce Type: new
Abstract: Predicting gene expression from H&E-stained histology images offers a scalable alternative to costly spatial transcriptomics, yet most existing methods...
By Zijun Gao, Chunbin Gu, Jinxi Xiang, Xiangde Luo, Pheng-Ann Heng
arXiv:2607. 22712v1 Announce Type: cross Abstract: Single-cell light microscopy images have become an important data source for characterizing cell phenotypes, but their complexity and heterogeneity pose challenges to high-throughput automated analysis.
By Yifan Shang (Department of Biomedical Engineering, The Chinese University of Hong Kong, Hong Kong, China, College of Computer Science and Electronic Engineering, Hunan University, Changsha, China), Jiahui Tan (College of Computer Science and Electronic Engineering, Hunan University, Changsha, China), Xiangxiang Zeng (College of Computer Science and Electronic Engineering, Hunan University, Changsha, China), Renjie Zhou (Department of Biomedical Engineering, The Chinese University of Hong Kong, Hong Kong, China)
arXiv:2507. 04704v3 Announce Type: replace-cross Abstract: Understanding how cellular morphology, gene expression, and spatial context jointly shape tissue function is a central challenge in biology.
By Zhenglun Kong, Mufan Qiu, John Boesen, Xiang Lin, Sukwon Yun, Tianlong Chen, Manolis Kellis, Marinka Zitnik
arXiv:2607. 14163v1 Announce Type: cross Abstract: Most single-cell foundation models are adapted from language models, representing each cell as a sequence of gene tokens.
By Ridvan Yesiloglu, Sakib Mostafa, James Zou, Ash Alizadeh, Jiajun Wu, Lei Xing, Ehsan Adeli, Md Tauhidul Islam
QCell is a query‑based model designed to improve overlapping cell instance segmentation in microscopy images. It introduces an instance recombination module that decomposes and recombines query representations in latent space, allowing the model to reason about entire cell structures even when they overlap. Additionally, a contrastive query alignment objective is used to learn distinctive instance features and separate overlapping cell queries. The authors also present a new Organoid dataset benchmark and demonstrate that QCell surpasses state‑of‑the‑art methods, achieving +2.2 AP and +2.7 AJI on the ISBI2014 benchmark.
By Yaroslav Prytula, Anton Popov, Dmytro Fishman
arXiv:2608.22619v1 Announce Type: cross
Abstract: Generative segmentation provides an alternative to direct pixel-wise prediction by operating on learned latent representations, but effective image-t...
By Md Maklachur Rahman, Md Hasan Al Banna, Saraf Anjum, Mahmudul Hasan, Tracy Hammond
Reconstructing lineages from live-imaging microscopy requires linking cell detections across time, including through cell divisions. A common approach is to construct a candidate graph and associate cell segmentations (nodes) across frames.
The paper presents a 3D foundation model for light sheet fluorescence microscopy (LSM) that is pretrained on a large curated set of 3D images from various organisms, stains, and imaging protocols. By jointly optimizing for masked reconstruction and image‑text alignment, the model learns transferable volumetric representations that dramatically reduce the need for annotated data. The pretrained backbone enables efficient few‑shot adaptation to downstream tasks such as segmentation, classification, and deblurring, consistently outperforming baselines according to standard metrics and expert evaluation.
By Adina Scheinfeld, Haotan Zhang, Shang Mu, Rudolf L. M. van Herten, Lucas Stoffl, Ali Erturk, Zhuhao Wu, Johannes C. Paetzold