The paper introduces two YOLOv11-based instance segmentation models that simultaneously perform wound boundary segmentation and wound classification across five clinically relevant wound types. Using a balanced dataset of 2,963 annotated images and data augmentation, the models achieve high performance, with YOLOv11x excelling in boundary segmentation and YOLOv11m and YOLOv11l leading in classification metrics. The lightweight YOLOv11n variant offers comparable accuracy with lower computational demands, making it suitable for resource-constrained clinical and remote care deployments.
By Mehedi Hasan Tusar, Fateme Fayyazbakhsh, Igor Melnychuk, Ming C. Leu
InstEditSeg is a generative framework that treats medical segmentation as an instruction-driven image editing task. Instead of producing binary masks, it renders a color-coded overlay on the original image guided by textual instructions, leveraging latent diffusion models to align with natural image distributions and reduce domain gaps. The method incorporates a DINOv3 visual encoder and a multi-scale feature pyramid fused into the diffusion U‑Net, and uses a dual‑branch classifier‑free guidance strategy to lower inference cost, achieving competitive accuracy on polyp and skin lesion datasets while improving cross‑domain generalization and multi‑lesion segmentation.
By Ziquan Liu, Zhewei Zhu, Xuyang Shi
arXiv:2609.00396v1 Announce Type: new
Abstract: Histopathological whole slide images (WSIs) are central to cancer diagnosis, but their gigapixel scale, tissue heterogeneity, weak slide-level supervis...
By Chad Wong, Sicheng Chen, Tianyi Zhang, Enhui Chai, Yueming Jin, Zeyu Liu, Fei Xia
The paper introduces an Early Intervention (EI) framework for multimodal medical image classification that addresses two key challenges: limited exploitation of complementary multimodal information and scarcity of labeled data for Vision Foundation Models (VFMs). EI treats one modality as the target and uses high‑level semantic tokens from other modalities as intervention tokens to guide the target’s embedding early in the process. The authors also propose Mixture of varied‑rank LoRAs (MoR) for efficient VFM adaptation, and demonstrate the method’s effectiveness on retinal, skin, and knee medical image datasets.
By Qijie Wei, Hailan Lin, Xirong Li
The paper proposes a two‑stage learning framework for multi‑organ segmentation that handles partially annotated datasets and domain shifts. First, the model learns accurate segmentations from available annotations to build robust feature representations. Second, it introduces learnable organ prototypes and a Sinkhorn‑triplet loss to enforce organ‑wise feature consistency across datasets, keeping embeddings of the same organ close while separating different organs, even when annotations are missing.
By Dakini Mallam Garba, Salim Abdou Daoura
RACR-MIL is a weakly‑supervised method for grading squamous cell carcinoma (SCC) from whole‑slide images, using an attention‑based multiple‑instance learning framework. It introduces a hybrid WSI graph to capture local tissue context and non‑local phenotypic dependencies, and applies rank‑ordering constraints on attention to prioritize higher‑grade tumor regions, mirroring pathologists’ diagnostic reasoning. The approach achieves state‑of‑the‑art performance, improving SCC grading accuracy by 3–9% over existing methods and up to 10% in tumor localization, and a pilot study showed pathologists reported increased grading efficiency in 60% of cases.
By Anirudh Choudhary, Mosbah Aouad, Krishnakant Saboo, Angelina Hwang, Jacob Kechter, Blake Bordeaux, Puneet Bhullar, David DiCaudo, Steven Nelson, Nneka Comfere, Emma Johnson, Olayemi Sokumbi, Jason Sluzevich, Leah Swanson, Dennis Murphree, Aaron Mangold, Ravishankar Iyer
arXiv:2607. 13237v1 Announce Type: cross Abstract: Precise spatial-temporal annotation of laparoscopic videos is time-consuming and requires expert knowledge.
By Manasa Dendukuri, Matjaz Jogan, Daniel A. Hashimoto, Guiqiu Liao
This study presents a clinically relevant framework for evaluating deep neural networks that segment lymphoma lesions in PET/CT images, addressing gaps such as out‑of‑distribution testing and comparison with expert annotators. Using 611 multi‑institutional cases, the authors assess four networks (ResUNet, SegResNet, DynUNet, SwinUNETR) with lesion‑specific metrics, detection criteria, and metabolic‑characteristic‑based thresholds, finding that models perform best on large, intense lesions. The work also demonstrates that network errors mirror those of physicians, highlighting shared challenges with small, faint lesions.
By Shadab Ahamed, Yixi Xu, Sara Kurkowska, Claire Gowdy, Joo H. O, Ingrid Bloise, Don Wilson, Patrick Martineau, Fran\c{c}ois B\'enard, Fereshteh Yousefirizi, Rahul Dodhia, Juan M. Lavista, William B. Weeks, Carlos F. Uribe, Arman Rahmim
arXiv:2608.23853v1 Announce Type: new
Abstract: The interpretation of endoscopic imagery in ulcerative colitis is complex and subjective, with variability in human assessment and subtle mucosal infla...
By Alexis Ivan Escamilla-Lopez, Gilberto Ochoa-Ruiz, Salvador Hinojosa, Sharib Ali
arXiv:2606. 19174v1 Announce Type: cross Abstract: Clinician-centered evaluation is critical for validating medical AI systems, especially in ultrasound imaging where quantitative metrics do not always capture clinical usability.
By Fangyijie Wang, Jianjun Yu, Wentao Shi, Haixia Huang, Ran Shi, Gu\'enol\'e Silvestre, Kathleen M. Curran
The paper presents a semi‑supervised biomedical image segmentation method that uses a diffusion‑based teacher–student framework. The teacher is pretrained via unsupervised diffusion reconstruction and then co‑trained with a student, leveraging supervised labels and cross pseudo‑supervision on unlabeled data. A multi‑round extension generates multiple stochastic reconstructions to further refine pseudo‑labels, achieving competitive or superior results on several 2D and 3D biomedical datasets, especially when labels are scarce.
By Luca Ciampi, Gabriele Lagani, Giuseppe Amato, Fabrizio Falchi
arXiv:2608. 10522v1 Announce Type: cross Abstract: While vision-language models dominate medical representation learning, unstructured text lacks the dense, quantitative diagnostic phenotypes inherent in structured clinical tables.
By Yingsheng Liu, Haiming Li, Jingmin Zhu, Jiajun Sun, Victoria Mar, Monika Janda, H. Peter Soyer, Zongyuan Ge, Zhen Yu