arXiv Computer Vision

Knowledge-structured and evidence-aware semantic self-distillation for glomerular pathology foundation model

The paper introduces GloSAGE, a semantic self‑distillation framework that leverages lesion profiles from a pretrained visual teacher to generate structured pathology descriptions for glomerular images. By selecting reliable image‑text anchors and synthesizing knowledge‑structured text, GloSAGE trains a frozen visual encoder with an intermediate semantic transfer layer, enabling zero‑shot lesion recognition, image‑text retrieval, and improved downstream tasks such as disease classification and renal function estimation. Experiments on the GloMillion dataset and seven cohorts demonstrate that GloSAGE outperforms its source visual model in most lesion‑recognition tasks and enhances grading accuracy while maintaining competitive performance on case‑level analyses.

arXiv AI
Sep 2

Benchmarking Vision-Language Models for Automated Pathology Diagnosis and Report Generation

arXiv:2609.00866v1 Announce Type: cross Abstract: The rapid advancement of vision-language models (VLMs) has accelerated progress in computational pathology; however, whole-slide image (WSI)-based pa...

By Yumi Lee, Harim Oh, Hyoryung Kim, Minji Kim, Eunsu Kim, Hyeseong Lee, Junya Fukuoka, Andrey Bychkov, Jijgee Munkhdelger, Rajiv Kumar Kaushal, Ayushi Sahay, Rajni Yadav, Bharathi Prabakaran, Sulen Sarioglu, Serdar Balc{\i}, Ilknur Turkmen, Yuri Tolkach, Christian Harder, Julian Westerdorf, Reinhard Buettner, Audun Ljone Henriksen, Sepp De Raedt, Byung Hyun Lee, Sungjin Lim, Joohoon Lee, Gwanghyun Kim, Se Young Chun, Suryakant Singh, Saarthak Kapse, Prateek Prasanna, Kyung A Kim, Yousun Kang, Sehwan Yoo, Sungman Hong, Shubham Innani, Michael Feldman, Spyridon Bakas, Ujjwal Baid, Prasad Dutande, Suhas Gajare, Bhakti Baheti, Serkan S\"okmen, Ece Tu\u{g}ba Cebeci, Ahmet Hal{\i}c{\i}, Musa Balc{\i}, Kardelen Pe\c{c}enek, Srividhya Sainath, Kyongseok Jang, Messi H. J. Lee, Noorul Wahab, Bodong Du, Jiaming Zhang, Qixiang Zhang, Jang-Hwan Choi, Sangjeong Ahn
arXiv Computer Vision
Oct 9

PathLang: A Language-Centered Benchmark for Vision-Language Models in Computational Pathology

PathLang is a new, language‑centered benchmark for vision‑language models in computational pathology. It keeps the underlying pathology slides, ground‑truth labels, and image‑text evaluation direction constant while systematically varying the diagnostic language used in prompts, reflecting how pathologists actually rephrase diagnoses. The benchmark covers four task families—zero‑shot classification with image‑text alignment, cross‑modal retrieval, paraphrase robustness, and open‑vocabulary diagnosis retrieval—and evaluates nine VLMs across five public datasets spanning four organs.

By Fanqi Cheng, Kuo Gong, Shangke Liu, Beidi Zhao, Junchao Zhu, Zheyu Zhu, Leiyue Zhao, Fengbei Liu, John Cannon, Gang Wang, Zu-hua Gao, Kenji Ikemura, Yihe Yang, Yaohong Wang, Yuankai Huo, Xiaoxiao Li, Mert R. Sabuncu, Ruining Deng
arXiv Machine Learning
Sep 24

FFM-CP: Cross-Backbone Fusion of Vision-Language Foundation Models for Few-Shot Computational Pathology

The paper introduces FFM-CP, a framework that fuses multiple pathology vision‑language foundation models for few‑shot learning. It aligns heterogeneous representations with an Orthogonal Procrustes transformation, then uses a unified graph to refine support‑image features and class prototypes across backbones. Experiments on six histopathology datasets show that FFM‑CP outperforms the best single adapted model in 50 of 54 few‑shot comparisons.

By Anh-Tien Nguyen, Trung DQ. Dang, Nghiem Tuong Diep, Bui Ngoc Han Nguyen, Tan-Ha Mai, Miriam Cindy Maurer, Phuong Hoa Nguyen, Thi Thuy Uyen Nguyen, Youngjun Park, Daniel Sonntag, Duy Minh Ho Nguyen, Anne-Christin Hauschild
arXiv AI
Aug 26

EviPathBench: Benchmarking Evidence Acquisition and Reasoning in Vision-Language Models for Whole-Slide Pathology

arXiv:2607.19261v4 Announce Type: replace-cross Abstract: Whole-slide image (WSI) diagnosis requires identifying diagnostically relevant regions, examining them across magnifications, and integrating...

By Dankai Liao, Tianyi Zhang, Yufeng Wu, Xinyue Zhang, Qiaochu Xue, Zeyu Liu, Dachun Zhao, Linghan Cai, Yueming Jin
arXiv AI
Oct 21

Gated Prototype Transfer for Zero-Support Medical Vision Language Model

The paper introduces Gated Knowledge‑Guided Prototype Transfer (GProtoT), a training‑free module that enhances zero‑support medical vision‑language models by transferring visual residuals from supported classes to missing ones using VLM similarity and clinical ontology distances. GProtoT employs an evidence gate to scale transfer based on semantic relevance, reducing negative transfer while modestly improving recall and accuracy in realistic one‑shot trials on MESSIDOR. The method requires no gradients, validation data, or extra inference, offering a low‑compute, accountable adaptation path for incomplete clinical supervision.

By Sumaiya Fazal, Rizwan Qureshi, Laleh Behjat, Samira Ebrahimi Kahou
arXiv AI
Sep 10

Semantic Context-aware mOdality fUsion Transformer (SCOUT): A Context-Aware Multimodal Transformer for Concept-Grounded Pathology Report Generation

SCOUT is a concept‑grounded multimodal transformer that generates whole‑slide pathology reports by integrating local histological patterns, whole‑slide context, and expert‑curated diagnostic concepts. It uses evolving visual representations and recursively updated slide‑ and concept‑conditioned representations, with separate attention pathways during decoding that are fused adaptively for each token. Evaluated on TCGA‑BRCA, HistAI, and REG‑2025, SCOUT outperformed existing methods, improving BLEU, METEOR, and ROUGE‑L scores and raising the Clinical Report Quality Score on REG‑2025.

By Suryakant Singh, Saarthak Kapse, Joel Saltz, Prateek Prasanna
arXiv Computer Vision
Sep 15

Accurate and Scalable Multimodal Pathology Retrieval via Attentive Vision-Language Alignment

arXiv:2510.23224v2 Announce Type: replace Abstract: The rapid digitization of histopathology slides has opened new opportunities for computational tools in clinical and research workflows. Content-ba...

By Hongyi Wang, Zhengjie Zhu, Junlin Hou, Jiabo Ma, Fang Wang, Yue Shi, Qiuyu Cai, Jili Wang, Bo Luo, Zhizhong Chai, Zhengyu Zhang, Li Liang, Xiuming Zhang, Yen-Wei Chen, Lanfen Lin, Hao Chen
arXiv AI
Aug 18

From Generalist to Specialist: A Context-Fusion Framework for Endoscopic Polyp Reporting with a Frozen VLM

arXiv:2608. 15580v1 Announce Type: new Abstract: Reliable endoscopic polyp reporting requires integrating quantitative lesion sizing, standardized Paris classification, and clinically meaningful morphological description within a single record.

By Ruijie Yang, Yan Zhu, Peiyao Fu, Siyuan Li, Te Luo, Zhihua Wang, Quanlin Li, Pinghong Zhou, Xian Yang, Shuo Wang
arXiv Computer Vision
Oct 22

Expandable Modality Experts for Medical Vision-Language Learning

The paper introduces Expandable Modality Experts, a medical vision‑language framework that uses an expandable bank of modality experts and a Multiway Transformer to combine shared visual computation with deterministic routing and a separate text pathway. It employs a modality‑aware visual tokenizer for masked pretraining on 19.4 million unpaired image rows across seven modalities, followed by contrastive alignment on 3.23 million image‑text pairs. With a ViT‑Large backbone, the method achieves state‑of‑the‑art results in 24 of 25 benchmark settings across nine modalities, including zero‑shot classification, linear probing, and retrieval tasks, while preserving existing representations.

By DM BAPPY, Eunsu Kim, Hanjoo Lee, Sung Hak Lee, Sangjeong Ahn